Cytoskeletal remodeling in cancer
J Aseervatham - Biology, 2020 - mdpi.com
Simple Summary Cell migration is an essential process from embryogenesis to cell death.
This is tightly regulated by numerous proteins that help in proper functioning of the cell. In …
This is tightly regulated by numerous proteins that help in proper functioning of the cell. In …
Targeting the cytoskeleton against metastatic dissemination
C Ruggiero, E Lalli - Cancer and Metastasis Reviews, 2021 - Springer
Cancer is a pathology characterized by a loss or a perturbation of a number of typical
features of normal cell behaviour. Indeed, the acquisition of an inappropriate migratory and …
features of normal cell behaviour. Indeed, the acquisition of an inappropriate migratory and …
Cytoskeletal dynamics in epithelial-mesenchymal transition: insights into therapeutic targets for cancer metastasis
A Datta, S Deng, V Gopal, KCH Yap, CE Halim, ML Lye… - Cancers, 2021 - mdpi.com
Simple Summary The epithelial to mesenchymal transition (EMT) is a well-documented
process in the study of cancer metastases. The cytoskeleton is an intricate network involved …
process in the study of cancer metastases. The cytoskeleton is an intricate network involved …
The actin cytoskeleton in normal and pathological cell motility
A Lambrechts, M Van Troys, C Ampe - … journal of biochemistry & cell biology, 2004 - Elsevier
Cell motility is crucial for tissue formation and for development of organisms. Later on cell
migration remains essential throughout the lifetime of the organism for wound healing and …
migration remains essential throughout the lifetime of the organism for wound healing and …
The cytoskeleton and cancer
A Hall - Cancer and Metastasis Reviews, 2009 - Springer
Cancer is a disease in which many of the characteristics of normal cell behavior are lost or
perturbed. Uncontrolled cell proliferation and inappropriate cell survival are common …
perturbed. Uncontrolled cell proliferation and inappropriate cell survival are common …
The role of actin dynamics and actin‐binding proteins expression in epithelial‐to‐mesenchymal transition and its association with cancer progression and evaluation …
M Izdebska, W Zielińska, D Grzanka… - BioMed research …, 2018 - Wiley Online Library
Metastasis causes death of 90% of cancer patients, so it is the most significant issue
associated with cancer disease. Thus, it is no surprise that many researchers are trying to …
associated with cancer disease. Thus, it is no surprise that many researchers are trying to …
Movers and shakers: cell cytoskeleton in cancer metastasis
CM Fife, JA McCarroll… - British journal of …, 2014 - Wiley Online Library
Metastasis is responsible for the greatest number of cancer deaths. Metastatic disease, or
the movement of cancer cells from one site to another, is a complex process requiring …
the movement of cancer cells from one site to another, is a complex process requiring …
Cytoskeletal changes in cell transformation and tumorigenesis
G Pawlak, DM Helfman - Current opinion in genetics & development, 2001 - Elsevier
Research during the past couple of years has provided important new information as to how
the actin cytoskeleton contributes to growth control in both normal and transformed cells …
the actin cytoskeleton contributes to growth control in both normal and transformed cells …
Role of cellular cytoskeleton in epithelial-mesenchymal transition process during cancer progression
BO Sun, Y Fang, Z Li, Z Chen… - Biomedical …, 2015 - spandidos-publications.com
Currently, cancer metastases remain a major clinical problem that highlights the importance
of recognition of the metastatic process in cancer diagnosis and treatment. A critical process …
of recognition of the metastatic process in cancer diagnosis and treatment. A critical process …
Actin binding proteins: their ups and downs in metastatic life
SR Gross - Cell adhesion & migration, 2013 - Taylor & Francis
In order to metastasize away from the primary tumor site and migrate into adjacent tissues,
cancer cells will stimulate cellular motility through the regulation of their cytoskeletal …
cancer cells will stimulate cellular motility through the regulation of their cytoskeletal …