[HTML][HTML] A critical evaluation of visual proportion of Gleason 4 and maximum cancer core length quantified by histopathologists

LM Carmona Echeverria, A Haider, A Freeman… - Scientific Reports, 2020 - nature.com
Gleason score 7 prostate cancer with a higher proportion of pattern 4 (G4) has been linked
to genomic heterogeneity and poorer patient outcome. The current assessment of G4 …

Oncologic outcomes of total length gleason pattern 4 on Biopsy in Men with Grade Group 2 prostate Cancer

M Perera, MJ Assel, NE Benfante, AJ Vickers… - The Journal of …, 2022 - auajournals.org
Purpose: Gleason Score 7 prostate cancer comprises a wide spectrum of disease risk, and
precise substratification is paramount. Our group previously demonstrated that the total …

Clinical usefulness of total length of Gleason pattern 4 on biopsy in men with grade group 2 prostate cancer

LW Dean, M Assel, DD Sjoberg, AJ Vickers… - The Journal of …, 2019 - auajournals.org
Purpose: To our knowledge the ideal methodology of quantifying secondary Gleason pattern
4 in men with Grade Group 2/Gleason score 3+ 4= 7 on biopsy remains unknown. We …

Volume of Gleason pattern 4 stratifies risk of metastasis and death in patients with Gleason score 3+ 5= 8/5+ 3= 8 positive prostate core biopsies

AM Acosta, ME Taplin, DA Mata, AV D'Amico… - Human Pathology, 2020 - Elsevier
Summary Implementation of Grade Groups (GrGrs) has been widely accepted for reporting
prostate cancer grade since the 2014 International Society of Urological Pathology …

Gleason score 3+ 4= 7 prostate cancer with minimal quantity of gleason pattern 4 on needle biopsy is associated with low-risk tumor in radical prostatectomy …

CC Huang, MX Kong, M Zhou… - The American journal …, 2014 - journals.lww.com
A modified Gleason grading system as proposed in the 2005 International Society of
Urological Pathology (ISUP) consensus meeting is the current grading system for prostate …

[HTML][HTML] Interobserver Reproducibility of Quantifying Gleason Pattern 4 Cancer in Prostate Biopsy: Implications for Clinical Practice

J Li, M Ettel, A Amin, R Bhalla, K Das… - Journal of Clinical …, 2023 - xiahepublishing.com
Methods Glass slides containing 55 biopsy cores of various amounts of GP4 were
distributed to 12 pathologists who quantified GP4 and determined the most common GP4 …

Combination of total length of Gleason pattern 4 and number of Gleason score 3+ 4= 7 cores detects similar outcome group to Gleason score 6 cancers among cases …

S Sato, T Kimura, H Onuma, Y Fukuda… - Pathology …, 2020 - Wiley Online Library
Expanding the inclusion criteria for active prostate cancer surveillance to include cases with
a Gleason score (GS) of 3+ 4= 7 has been discussed. GS 3+ 4= 7 cases with a percentage …

Prognostic value of percent Gleason grade 4 at prostate biopsy in predicting prostatectomy pathology and recurrence

AI Cole, TM Morgan, DE Spratt, GS Palapattu… - The Journal of …, 2016 - auajournals.org
Purpose: The importance of primary Gleason grade among men with Gleason score 7
disease has been well-defined. However, this dichotomization may oversimplify the …

[HTML][HTML] Quantification of Gleason Pattern 4 at MRI-Guided Biopsy to Predict Adverse Pathology at Radical Prostatectomy in Intermediate-Risk Prostate Cancer …

H Kamecki, Ł Mielczarek, S Szempliński, M Dębowska… - Cancers, 2023 - mdpi.com
Simple Summary The amount of Gleason pattern 4 (GP4) in biopsy material may be used for
individual risk stratification in prostate cancer patients. The utility of this parameter is …

[HTML][HTML] Gene-expression analysis of gleason grade 3 tumor glands embedded in low-and high-risk prostate cancer

AM Hoogland, R Böttcher, E Verhoef, G Jenster… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The Gleason score (GS) of prostate cancer on diagnostic biopsies is an important parameter
for therapeutic decision-making. Biopsy GS under-estimates the actual GS at radical …