Advances in exercise to alleviate sarcopenia in older adults by improving mitochondrial dysfunction

Y Zhu, X Zhou, A Zhu, S Xiong, J Xie, Z Bai - Frontiers in Physiology, 2023 - frontiersin.org
Sarcopenia is a chronic degenerative disease affecting primarily older adults. A growing
aging population is gradually increasing the number of patients suffering from sarcopenia …

[HTML][HTML] Exercise and mitochondrial mechanisms in patients with sarcopenia

H Alizadeh Pahlavani, I Laher, B Knechtle… - Frontiers in …, 2022 - frontiersin.org
Sarcopenia is a severe loss of muscle mass and functional decline during aging that can
lead to reduced quality of life, limited patient independence, and increased risk of falls. The …

[HTML][HTML] Regulation of mitochondrial dynamic equilibrium by physical exercise in Sarcopenia: A systematic review

YF Long, SKH Chow, C Cui, RMY Wong, L Qin… - Journal of orthopaedic …, 2022 - Elsevier
Background Sarcopenia is a hallmark of the ageing process, which is characterized by the
decline in muscle mass and strength. Growing evidence indicates that mitochondria …

Targeting mitochondrial quality control for treating sarcopenia: lessons from physical exercise

A Picca, R Calvani, C Leeuwenburgh… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Mitochondrial dysfunction is a hallmark of aging and hence is a candidate
target for intervention. Sarcopenia of aging is a prevalent condition and is associated with …

Mitochondrial impairment in sarcopenia

F Bellanti, A Lo Buglio, G Vendemiale - Biology, 2021 - mdpi.com
Simple Summary With old age, the strength and size of our muscles worsens with time,
affecting our ability to carry out daily activities. Muscle wasting may be more dangerous for …

Exercise rescues mitochondrial coupling in aged skeletal muscle: a comparison of different modalities in preventing sarcopenia

C Harper, V Gopalan, J Goh - Journal of translational medicine, 2021 - Springer
Skeletal muscle aging is associated with a decline in motor function and loss of muscle
mass-a condition known as sarcopenia. The underlying mechanisms that drive this …

Aging-induced Sarcopenia and Exercise.

JW Heo, MH No, DH Min, JH Kang… - The Official Journal of the …, 2017 - ajkinesiol.org
PURPOSE Aging is associated with a progressive loss of skeletal muscle mass and strength
as well as physical performance called sarcopenia. Sarcopenia is one of the leading causes …

Exercise-induced autophagy suppresses sarcopenia through Akt/mTOR and Akt/FoxO3a signal pathways and AMPK-mediated mitochondrial quality control

Z Zeng, J Liang, L Wu, H Zhang, J Lv… - Frontiers in physiology, 2020 - frontiersin.org
Exercise training is one of the most effective interventional strategies for sarcopenia in aged
people. Nevertheless, the underlying mechanisms are not well recognized. Increasing …

Mitochondrial ROS and aging: understanding exercise as a preventive tool

HS Brunetta, AM Holwerda, LJC van Loon… - Journal of Science in …, 2020 - Springer
Sarcopenia, which is characterized by reduction in muscle mass and strength, contributes to
several age-related conditions, including insulin resistance and frailty. Despite the …

[HTML][HTML] Mitochondria as a target for mitigating sarcopenia

PM Coen, RV Musci, JM Hinkley, BF Miller - Frontiers in Physiology, 2019 - frontiersin.org
Sarcopenia is the loss of muscle mass, strength, and physical function that is characteristic
of aging. The progression of sarcopenia is gradual but may be accelerated by periods of …