Autoantibodies-enemies, and/or potential allies?
H Ma, C Murphy, CE Loscher… - Frontiers in Immunology, 2022 - frontiersin.org
Autoantibodies are well known as potentially highly harmful antibodies which attack the host
via binding to self-antigens, thus causing severe associated diseases and symptoms (eg …
via binding to self-antigens, thus causing severe associated diseases and symptoms (eg …
Autoantibody-based diagnostic biomarkers: Technological approaches to discovery and validation
F Aziz, M Smith, JM Blackburn - Autoantibodies and cytokines, 2018 - books.google.com
Autoantibodies produced against self-antigens, or 'autoantigens', result from a loss of
selftolerance triggered by genetic and/or environmental factors which induce the immune …
selftolerance triggered by genetic and/or environmental factors which induce the immune …
Toward a new autoantibody diagnostic orthodoxy: understanding the bad, good and indifferent
MJ Fritzler - Autoimmunity Highlights, 2012 - Springer
Rapid advances in diagnostic technologies used to detect autoantibodies have made it
difficult for even the most modern laboratory to keep abreast of the changing approaches …
difficult for even the most modern laboratory to keep abreast of the changing approaches …
Autoantibodies targeting intracellular and extracellular proteins in autoimmunity
PD Burbelo, MJ Iadarola, JM Keller… - Frontiers in …, 2021 - frontiersin.org
Detecting autoantibodies provides foundational information for the diagnosis of most
autoimmune diseases. An important pathophysiological distinction is whether …
autoimmune diseases. An important pathophysiological distinction is whether …
Definition of human autoimmunity—autoantibodies versus autoimmune disease
The critical function of the immune system is to discriminate self from non-self. Tolerance
against self-antigens is a highly regulated process and, in order to maintain it, the immune …
against self-antigens is a highly regulated process and, in order to maintain it, the immune …
Autoantibody discovery, assay development and adoption: death valley, the sea of survival and beyond
Dating to the discovery of the Lupus Erythematosus (LE) cell in 1948, there has been a
dramatic growth in the discovery of unique autoantibodies and their cognate targets, all of …
dramatic growth in the discovery of unique autoantibodies and their cognate targets, all of …
Anti-cancer auto-antibodies: Roles, applications and open issues
Simple Summary Cancer is one of the main causes of death worldwide and early detection
is crucial for effective treatment. Scientists have therefore focused on the identification of …
is crucial for effective treatment. Scientists have therefore focused on the identification of …
Autoantibodies 2015: from diagnostic biomarkers toward prediction, prognosis and prevention
J Damoiseaux, LE Andrade, MJ Fritzler… - Autoimmunity reviews, 2015 - Elsevier
Abstract At the 12th International Workshop on Autoantibodies and Autoimmunity (IWAA),
organized in August 2014 in Sao Paulo, Brazil, more than 300 autoimmunologists gathered …
organized in August 2014 in Sao Paulo, Brazil, more than 300 autoimmunologists gathered …
An updated advance of autoantibodies in autoimmune diseases
Autoantibodies are abnormal antibodies which are generated by pathogenic B cells when
targeting an individual's own tissue. Autoantibodies have been identified as a symbol of …
targeting an individual's own tissue. Autoantibodies have been identified as a symbol of …
Mechanisms of autoantibody-induced pathology
RJ Ludwig, K Vanhoorelbeke, F Leypoldt… - Frontiers in …, 2017 - frontiersin.org
Autoantibodies are frequently observed in healthy individuals. In a minority of these
individuals, they lead to manifestation of autoimmune diseases, such as rheumatoid arthritis …
individuals, they lead to manifestation of autoimmune diseases, such as rheumatoid arthritis …