Cell fusion is a biological mechanism crucial for physiological processes, such as
fertilization and placentation, wound healing, and tissue regeneration as well as …

Although molecular mechanisms and signaling pathways driving invasion and metastasis
have been studied for many years, the origin of the population of metastatic cells within the …

The natural phenomenon of cell–cell fusion does not only take place in physiological
processes, such as placentation, myogenesis, or osteoclastogenesis, but also in …

Cell fusion is involved in many physiological and pathological processes, including gamete
binding, and cancer development. The basic processes of cell fusion include membrane …

Fusion among different cell populations represents a rare process that is mediated by both
intrinsic and extracellular events. Cellular hybrid formation is relayed by orchestrating tightly …

Aneuploidy, metastasis formation, and drug resistance are major issues to overcome in most
cancers. If there exists common underlying proceedings for the formation of these …

According to estimates from the International Agency for Research on Cancer, by the year
2030 there will be 22 million new cancer cases and 13 million deaths per year. The main …

Mammalian life begins with a cell–cell fusion event, ie the fusion of the spermatozoid with
the oocyte and needs further cell–cell fusion processes for the development, growth, and …

Cellular fusion eg between cancer cells and normal cells represents a stepwise process that
is tightly regulated. During a pre-hybrid preparation program somatic cells and/or cancer …

Metastasis is the leading cause of cancer death and can be realized through the
phenomenon of tumor cell fusion. The fusion of tumor cells with other tumor or normal cells …