Oxidative stress generates a large amount of reactive oxygen species (ROS) and affects
sperm quality via damaging sperm DNA and compromising the intracellular homeostasis in …

Busulfan is a widely used chemotherapeutic drug for chronic myelogenous leukemia and
bone marrow transplantation. As a cell cycle nonspecific alkylation agent, busulfan has a …

Spermatozoa (SPZ) are sensitive to stressful conditions, particularly oxidative stress, which
alters their quality; thus, the use of protective molecules as an antioxidant is encouraged …

Reactive oxygen species (ROS) are essential for sperm physiological functions such as
capacitation, hyperactivation, and acrosome reaction, on the one hand, and for stimulating …

Mammalian spermatozoa are highly susceptible to reactive oxygen species (ROS) stress.
The aim of the present study was to investigate whether and how melatonin protects rabbit …

It is assumed somatic cells can die in the apoptotic, the autophagic, or the necrotic way;
however, the mechanisms of sperm death are not clear. Here, ejaculated human …

Objective To study the damage of mitochondrial function of sperm induced by reactive
oxygen species (ROS), and the protection of melatonin (MLT) against the damage. Methods …

Spermatogenesis, an intricate process occurring in the testis, is responsible for ongoing
production of spermatozoa and thus the cornerstone of lifelong male fertility. In the testis …

Sperm cells can be damaged during the semen cryopreservation process, decreasing their
fertilizing ability. Physical damage and oxidative stress may occur during the freeze–thawing …

Decline in semen quality has become a global public health concern. Psychological stress is
common in the current modern society and is associated with semen decline. Increasing …