Cell entry of the pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
is mediated by its spike protein S. As a main antigenic determinant, S protein is in focus of …

A distinctive feature of the SARS-CoV-2 spike protein is its ability to efficiently fuse cells, thus
producing syncytia found in COVID-19 patients. This commentary proposes how this ability …

The trimeric severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein
(S) is the sole viral protein responsible for both viral binding to a host cell and the membrane …

Abstract Background The novel SARS-CoV-2 has quickly become a global pandemic since
the first reported case in December 2019, with the virus infecting millions of people to date …

SARS‐CoV spike (S) protein‐mediated cell fusion is important for the viral entry mechanism
and identification of SARS‐CoV entry inhibitors. In order to avoid the high risks involved in …

Severe cases of COVID‐19 are associated with extensive lung damage and the presence of
infected multinucleated syncytial pneumocytes. The viral and cellular mechanisms …

Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which
causes coronavirus disease 2019 (COVID-19), is initiated by the virus spike (S) glycoprotein …

The COVID pandemic fueled by emerging SARS-CoV-2 new variants of concern remains a
major global health concern, and the constantly emerging mutations present challenges to …

The recent COVID-19 pandemic poses a serious threat to global public health, thus there is
an urgent need to define the molecular mechanisms involved in SARS-CoV-2 spike (S) …

The most severe forms of coronavirus disease 2019 (COVID‐19) are often associated with
the presence of syncytia in the lungs resulting from cell–cell fusion mediated by the SARS …