Machine learning using intrinsic genomic signatures for rapid classification of novel pathogens: COVID-19 case study

GS Randhawa, MPM Soltysiak, H El Roz… - Plos one, 2020 - journals.plos.org
The 2019 novel coronavirus (renamed SARS-CoV-2, and generally referred to as the COVID-
19 virus) has spread to 184 countries with over 1.5 million confirmed cases. Such major viral …

ViraMiner: Deep learning on raw DNA sequences for identifying viral genomes in human samples

A Tampuu, Z Bzhalava, J Dillner, R Vicente - PloS one, 2019 - journals.plos.org
Despite its clinical importance, detection of highly divergent or yet unknown viruses is a
major challenge. When human samples are sequenced, conventional alignments classify …

[PDF][PDF] Accurate identification of sars-cov-2 from viral genome sequences using deep learning

A Lopez-Rincon, A Tonda, L Mendoza-Maldonado… - BioRxiv, 2020 - academia.edu
One of the reasons for the fast spread of SARS-CoV-2 is the lack of accuracy in detection
tools in the clinical field. Molecular techniques, such as quantitative real-time RT-PCR and …

Enabling artificial intelligence for genome sequence analysis of COVID-19 and alike viruses

I Ahmed, G Jeon - Interdisciplinary sciences: computational life sciences, 2022 - Springer
Recent pandemic of COVID-19 (Coronavirus) caused by severe acute respiratory syndrome
Coronavirus 2 (SARS-CoV-2) has been growing lethally with unusual speed. It has infected …

Genome Detective Coronavirus Typing Tool for rapid identification and characterization of novel coronavirus genomes

S Cleemput, W Dumon, V Fonseca… - …, 2020 - academic.oup.com
Genome detective is a web-based, user-friendly software application to quickly and
accurately assemble all known virus genomes from next-generation sequencing datasets …

Classification and specific primer design for accurate detection of SARS-CoV-2 using deep learning

A Lopez-Rincon, A Tonda, L Mendoza-Maldonado… - Scientific reports, 2021 - nature.com
In this paper, deep learning is coupled with explainable artificial intelligence techniques for
the discovery of representative genomic sequences in SARS-CoV-2. A convolutional neural …

Assignment of epidemiological lineages in an emerging pandemic using the pangolin tool

Á O'Toole, E Scher, A Underwood, B Jackson… - Virus …, 2021 - academic.oup.com
The response of the global virus genomics community to the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) pandemic has been unprecedented, with significant …

Betacoronavirus Genomes: How Genomic Information has been Used to Deal with Past Outbreaks and the COVID-19 Pandemic

A Llanes, CM Restrepo, Z Caballero, S Rajeev… - International journal of …, 2020 - mdpi.com
In the 21st century, three highly pathogenic betacoronaviruses have emerged, with an
alarming rate of human morbidity and case fatality. Genomic information has been widely …

Interpretable detection of novel human viruses from genome sequencing data

JM Bartoszewicz, A Seidel… - NAR genomics and …, 2021 - academic.oup.com
Viruses evolve extremely quickly, so reliable methods for viral host prediction are necessary
to safeguard biosecurity and biosafety alike. Novel human-infecting viruses are difficult to …

Virtifier: a deep learning-based identifier for viral sequences from metagenomes

Y Miao, F Liu, T Hou, Y Liu - Bioinformatics, 2022 - academic.oup.com
Motivation Viruses, the most abundant biological entities on earth, are important
components of microbial communities, and as major human pathogens, they are …