Magnetic glyco-nanoparticles: a tool to detect, differentiate, and unlock the glyco-codes of cancer via magnetic resonance imaging

K El-Boubbou, DC Zhu, C Vasileiou… - Journal of the …, 2010 - ACS Publications
Within cancer, there is a large wealth of diversity, complexity, and information that nature has
engineered rendering it challenging to identify reliable detection methods. Therefore, the …

Magnetic glyco-nanoparticles: a unique tool for rapid pathogen detection, decontamination, and strain differentiation

K El-Boubbou, C Gruden, X Huang - Journal of the American …, 2007 - ACS Publications
Many pathogens use mammalian cell surface carbohydrates as anchors for attachments,
which subsequently results in infection. The unique combination of magnetic nanoparticles …

Glyconanoparticles as multifunctional and multimodal carbohydrate systems

M Marradi, F Chiodo, I García, S Penadés - Chemical Society Reviews, 2013 - pubs.rsc.org
The quest for the construction of multivalent carbohydrate systems, with precise geometries
that are highly efficient in interacting with carbohydrate binding proteins, has been a goal of …

[PDF][PDF] Site-specific multivalent carbohydrate labeling of quantum dots and magnetic beads

XL Sun, W Cui, C Haller, EL Chaikof - ChemBioChem, 2004 - academia.edu
Cell-surface carbohydrates act as receptors for a variety of protein ligands and thereby play
a significant role in a wide range of biological processes, including immune-recognition …

Hydrazide Functionalized Core–Shell Magnetic Nanocomposites for Highly Specific Enrichment of N-Glycopeptides

L Liu, M Yu, Y Zhang, C Wang, H Lu - ACS applied materials & …, 2014 - ACS Publications
In view of the biological significance of glycosylation for human health, profiling of
glycoproteome from complex biological samples is highly inclined toward the discovery of …

[HTML][HTML] Glyconanomaterials: Emerging applications in biomedical research

X Chen, O Ramström, M Yan - Nano research, 2014 - Springer
Carbohydrates constitute the most abundant organic matter in nature, serving as structural
components and energy sources, and mediating a wide range of cellular activities. The …

Magnetic nanoparticles with diblock glycopolymer shells give lectin concentration-dependent MRI signals and selective cell uptake

JS Basuki, L Esser, HTT Duong, Q Zhang, P Wilson… - Chemical …, 2014 - pubs.rsc.org
Multivalent glycopolymers exhibit a strong affinity for specific lectin proteins depending on
their specific carbohydrate functionality. In this work, we report a facile one-pot synthesis of …

Iron oxide/gold core/shell nanoparticles for ultrasensitive detection of carbohydrate− protein interactions

CH Liang, CC Wang, YC Lin, CH Chen… - Analytical …, 2009 - ACS Publications
Changes in the expression of cell surface glycan are often associated with malignant
metastasis. The expression level may be dramatically enhanced during tumor progression …

Surface design of magnetic nanoparticles for stimuli-responsive cancer imaging and therapy

T Kang, F Li, S Baik, W Shao, D Ling, T Hyeon - Biomaterials, 2017 - Elsevier
Magnetic nanoparticles (MNPs) have been extensively studied for their potential
applications to cancer diagnosis and treatment. However, various obstacles limit the use of …

Sugar/gadolinium-loaded gold nanoparticles for labelling and imaging cells by magnetic resonance imaging

A Irure, M Marradi, B Arnáiz, N Genicio, D Padro… - Biomaterials …, 2013 - pubs.rsc.org
Targeted magnetic resonance imaging (MRI) probes for selective cell labelling and tracking
are highly desired. We here present biocompatible sugar-coated paramagnetic Gd-based …