A 4-stage colon simulator and a cell culture-based human intestinal epithelial function
model were combined to study the effects of a soluble fiber, polydextrose (PDX), on …

Dietary fibre has been proposed to decrease risk for colon cancer by altering the
composition of intestinal microbes or their activity. In the present study, the changes in …

In this placebo-controlled, double-blind, crossover human feeding study, the effects of
polydextrose (PDX; 8 g/d) on the colonic microbial composition, immune parameters, bowel …

Polyphenols are natural compounds with high structural diversity whose common
occurrence in plants renders them intrinsic dietary components. They are known to be …

High level of dietary fiber has been epidemiologically linked to protection against the risk for
developing colon cancer. The mechanisms of this protection are not clear. Fermentation of …

Cyclooxygenases (Cox)-1 and-2 play important roles in gastrointestinal health; chronic
overexpression of Cox-2 is associated with inflammatory and cancerous disease, whereas …

This study focused on the effects of candidate prebiotics polydextrose (PDX) and xylitol on
the microbial community and its metabolic activity in a colon simulator. A semicontinuous …

The positive association of decreased risk of colorectal cancer with nonsteroidal
antiinflammatory drug (NSAID) use, combined with the observation that cyclooxygenase …

Polska Platforma Medyczna Polish Platform of Medical Research https://ppm.edu.pl
Repozytorium Pomorskiego Uniwersytetu Medyczneg Page 1 Polska Platforma Medyczna Polish …

Background & Aims: Evidence is accumulating that inhibitors of cyclooxygenase (COX)-2
activity are useful for preventing human colon cancer. Therefore, it is important to determine …