Sequential model selection-based segmentation to detect DNA copy number variation
Array-based CGH experiments are designed to detect genomic aberrations or regions of
DNA copy-number variation that are associated with an outcome, typically a state of disease …
DNA copy-number variation that are associated with an outcome, typically a state of disease …
A Bayesian Analysis of Copy Number Variations in Array Comparative Genomic Hybridization Data
Abstract Array Comparative Genomic Hybridization (CGH) has been widely used for
detecting genomic copy number variations (CNVs). The central goal of array CGH data …
detecting genomic copy number variations (CNVs). The central goal of array CGH data …
Bayesian random segmentation models to identify shared copy number aberrations for array CGH data
Array-based comparative genomic hybridization (aCGH) is a high-resolution, high-
throughput technique for studying the genetic basis of cancer. The resulting data consist of …
throughput technique for studying the genetic basis of cancer. The resulting data consist of …
Improved statistical analysis for array CGH-based DNA copy number aberrations
H Jiang, ZZ Zhu, Y Yu, S Lin, L Hou - Cancer Informatics, 2011 - journals.sagepub.com
Array-based comparative genomic hybridization (aCGH) allows measuring DNA copy
number at the whole genome scale. In cancer studies, one may be interested in identifying …
number at the whole genome scale. In cancer studies, one may be interested in identifying …
Signal extraction and breakpoint identification for array CGH data using robust state space model
Array comparative genomic hybridization (CGH) is a high resolution technique to assess
DNA copy number variation. Identifying breakpoints where copy number changes will …
DNA copy number variation. Identifying breakpoints where copy number changes will …
Integrating copy number polymorphisms into array CGH analysis using a robust HMM
SP Shah, X Xuan, RJ DeLeeuw, M Khojasteh… - …, 2006 - academic.oup.com
Motivation: Array comparative genomic hybridization (aCGH) is a pervasive technique used
to identify chromosomal aberrations in human diseases, including cancer. Aberrations are …
to identify chromosomal aberrations in human diseases, including cancer. Aberrations are …
A statistical change point model approach for the detection of DNA copy number variations in array CGH data
Array comparative genomic hybridization (aCGH) provides a high-resolution and high-
throughput technique for screening of copy number variations (CNVs) within the entire …
throughput technique for screening of copy number variations (CNVs) within the entire …
Detecting and analyzing copy number alternations in array-based cgh data
Copy number changes or alterations are a form of genetic variation in the human genome.
Genomic DNA copy number alterations (CNAs) are associated with the development and …
Genomic DNA copy number alterations (CNAs) are associated with the development and …
Experimental designs for array comparative genomic hybridization technology
SK McDonnell, SM Riska, EW Klee… - … and genome research, 2013 - karger.com
Array comparative genomic hybridization (aCGH) technology is commonly used to estimate
genome-wide copy-number variation and to evaluate associations between copy number …
genome-wide copy-number variation and to evaluate associations between copy number …
A comparison study: applying segmentation to array CGH data for downstream analyses
H Willenbrock, J Fridlyand - Bioinformatics, 2005 - academic.oup.com
Motivation: Array comparative genomic hybridization (CGH) allows detection and mapping
of copy number of DNA segments. A challenge is to make inferences about the copy number …
of copy number of DNA segments. A challenge is to make inferences about the copy number …