Innate immunity comprises several inflammation-related modulatory pathways which receive
signals from an array of membrane-bound and cytoplasmic pattern recognition receptors …

Cytosolic NOD-like receptors (NLRs) have been associated with human diseases including
infections, cancer, and autoimmune and inflammatory disorders. These innate immune …

Members of the family of NOD-like receptors (NLRs) play essential roles in innate immunity
by detecting intracellular 'pathogen-associated molecular patterns'(PAMPs) and 'danger …

The NOD-like receptors (NLRs) are a specialized group of intracellular receptors that
represent a key component of the host innate immune system. Since the discovery of the first …

Nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs) are a family of
intracellular sensors that have key roles in innate immunity and inflammation. Whereas …

Background Recently, many studies have reported that some botanicals and natural
products were able to regulate NOD-like receptor signaling. NOD-like receptors (NLRs) …

NOD1 {nucleotide-binding oligomerization domain 1; NLRC [NOD-LRR (leucine-rich repeat)
family with CARD (caspase recruitment domain) 1]} and NOD2 (NLRC2) are among the …

Innate immunity is a primary defense system against microbial infections. Innate immune
pattern recognition receptors (PRRs) play pivotal roles in detection of invading pathogens …

The innate immune system comprises several classes of pattern‐recognition receptors,
including Toll‐like receptors (TLRs) and nucleotide binding and oligomerization domain‐like …

NLRs have been shown in a number of models to protect against microbial infection through
their ability to participate in “pattern recognition” and their triggering of inflammatory …