Bacteriophages of the human gut: the “known unknown” of the microbiome

AN Shkoporov, C Hill - Cell host & microbe, 2019 - cell.com
The human gut microbiome is a dense and taxonomically diverse consortium of
microorganisms. While the bacterial components of the microbiome have received …

Shining light on human gut bacteriophages

E Guerin, C Hill - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
The human gut is a complex environment that contains a multitude of microorganisms that
are collectively termed the microbiome. Multiple factors have a role to play in driving the …

Probing the “dark matter” of the human gut phageome: Culture assisted metagenomics enables rapid discovery and host-linking for novel bacteriophages

CB Fitzgerald, AN Shkoporov, A Upadrasta… - Frontiers in cellular …, 2021 - frontiersin.org
Recent years have been marked by the growing interest towards virulent and temperate
bacteriophage populations inhabiting the human lower gastrointestinal tract–the gut …

The human gut phageome: origins and roles in the human gut microbiome

EM Townsend, L Kelly, G Muscatt, JD Box… - Frontiers in cellular …, 2021 - frontiersin.org
The investigation of the microbial populations of the human body, known as the microbiome,
has led to a revolutionary field of science, and understanding of its impacts on human …

Factors affecting variation of the human gut phageome

CA Tobin, C Hill, AN Shkoporov - Annual Review of …, 2023 - annualreviews.org
The gut microbiome is a dense and metabolically active consortium of microorganisms and
viruses located in the lower gastrointestinal tract of the human body. Bacteria and their …

[HTML][HTML] New insights into intestinal phages

R Sausset, MA Petit, V Gaboriau-Routhiau… - Mucosal …, 2020 - Elsevier
The intestinal microbiota plays important roles in human health. This last decade, the viral
fraction of the intestinal microbiota, composed essentially of phages that infect bacteria …

Healthy human gut phageome

P Manrique, B Bolduc, ST Walk… - Proceedings of the …, 2016 - National Acad Sciences
The role of bacteriophages in influencing the structure and function of the healthy human gut
microbiome is unknown. With few exceptions, previous studies have found a high level of …

The human gut phage community and its implications for health and disease

P Manrique, M Dills, MJ Young - Viruses, 2017 - mdpi.com
In this review, we assess our current understanding of the role of bacteriophages infecting
the human gut bacterial community in health and disease. In general, bacteriophages …

Ménage à trois in the human gut: interactions between host, bacteria and phages

MK Mirzaei, CF Maurice - Nature Reviews Microbiology, 2017 - nature.com
The human gut is host to one of the densest microbial communities known, the gut
microbiota, which contains bacteria, archaea, viruses, fungi and other microbial eukaryotes …

Phages in the gut ecosystem

M Zuppi, HL Hendrickson, JM O'Sullivan… - Frontiers in cellular and …, 2022 - frontiersin.org
Phages, short for bacteriophages, are viruses that specifically infect bacteria and are the
most abundant biological entities on earth found in every explored environment, from the …