Inflammatory bowel diseases (IBD) such as Crohn's Disease (CD) and Ulcerative Colitis
(UC) are chronic, progressive, and relapsing disorders of the gastrointestinal tract (GIT) …

The incidence and prevalence of inflammatory bowel disease (IBD) increases steadily
worldwide. There is an urgent need for effective and safe IBD therapies. Accelerated …

Epithelial restitution is an essential process that is required to repair barrier function at
mucosal surfaces following injury. Prolonged breaches in epithelial barrier function result in …

Treatment of inflammatory bowel disease at present mainly targets mediators of
inflammation to stop or suppress pro-inflammatory processes. Typical examples are …

Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, is a
chronic inflammatory condition of the gastrointestinal (GI) tract. Currently, it is treated with …

Background Although in most patients with inflammatory bowel diseases, conservative
therapy is successful, a significant proportion of patients still require surgery once in their …

Anti‐inflammatory compounds, delivered as a payload to the gastrointestinal tract (GIT) by
carriers, still cannot treat inflammatory bowel diseases without avoiding side effects. Here …

Lipid mediators are important messengers in many physiological processes. The pro-
inflammatory effect of many prostaglandins, derived from the essential arachidonic acid, are …

Active resolution of acute inflammation is a previously unrecognized interface between
innate and adaptive immunity. Once thought to be a passive process, the resolution of …

Medical treatment has progressed significantly over the past decade towards achieving and
maintaining clinical remission in patients with refractory ulcerative colitis (UC). Proposed …