The role of novel biomarker HE4 in endometrial cancer: a case control prospective study

R Angioli, F Plotti, S Capriglione, R Montera, P Damiani… - Tumor Biology, 2013 - Springer
The aim of the study was to explore the clinical value of serum human epididymis secretory
protein E4 (HE4) and CA125 in endometrial carcinoma. From January 2010 to April 2012 …

Diagnostic value of serum HE4 in endometrial cancer: a meta-analysis

Y Bie, Z Zhang - World journal of surgical oncology, 2014 - Springer
Background Endometrial cancer (EC) is a common female malignant cancer. The age of
incidence has become younger than before. If the diagnosis is during stage I, then the …

Utility of tumor marker HE4 as prognostic factor in endometrial cancer: a single-center controlled study

S Capriglione, F Plotti, A Miranda, R Ricciardi… - Tumor Biology, 2015 - Springer
This study aims to investigate the correlation between preoperative human epididymis
protein 4 (HE4) levels, endometrial cancer (EC) staging, and ideal cutoff for stage prediction …

Significance of HE4 estimation in comparison with CA125 in diagnosis of ovarian cancer and assessment of treatment response

EO Hamed, H Ahmed, OB Sedeek, AM Mohammed… - Diagnostic …, 2013 - Springer
Background Human epididymis protein 4 (HE4) is a novel and specific biomarker for ovarian
cancer. The aim of this study is to evaluate a new tumor marker, HE4, in comparison with …

HE4 is an independent prognostic marker in endometrial cancer patients

I Mutz-Dehbalaie, D Egle, S Fessler, M Hubalek… - Gynecologic …, 2012 - Elsevier
OBJECTIVE: To evaluate the prognostic value of pretherapeutic serum HE4 in endometrial
cancer in comparison to CA125. METHODS: HE4 and CA125 serum levels were analyzed …

Serum HE4 concentration is not dependent on menstrual cycle or hormonal treatment among endometriosis patients and healthy premenopausal women

M Hallamaa, P Suvitie, K Huhtinen, J Matomäki… - Gynecologic …, 2012 - Elsevier
OBJECTIVE: Human epididymal secretory protein E4 (HE4) is a new promising tumor
marker developed for the diagnostics and follow up of ovarian cancer. It has yet to become …

Utility of a novel serum tumor biomarker HE4 in patients with endometrioid adenocarcinoma of the uterus

RG Moore, AK Brown, MC Miller, D Badgwell, Z Lu… - Gynecologic …, 2008 - Elsevier
OBJECTIVE: Tumor markers with increased sensitivity and specificity for endometrial cancer
are needed to help monitor response to therapy and to detect recurrent disease. Currently …

Comparison of ovarian cancer markers in endometriosis favours HE4 over CA125

B McKINNON, MD Mueller… - Molecular …, 2015 - spandidos-publications.com
Endometriosis is a gynaecological condition with an associated chronic inflammatory
response. The ectopic growth of 'lesions', consisting of endometrial cells outside the uterine …

[HTML][HTML] Value of HE4 combined with cancer antigen 125 in the diagnosis of endometrial cancer

C Dong, P Liu, C Li - Pakistan journal of medical sciences, 2017 - ncbi.nlm.nih.gov
Objective: To investigate the clinical significance of human epididymal secretory protein E4
(HE4) in combination with cancer antigen 125 (CA125) in the diagnosis of endometrial …

A critical review on HE4 performance in endometrial cancer: where are we now?

R Angioli, A Miranda, A Aloisi, R Montera… - Tumor Biology, 2014 - Springer
To date, no good marker for endometrial cancer (EC) that may be routinely used in clinical
practice for diagnosis, prognosis and monitoring is available; besides the use of tumour …