The worldwide epidemic of metabolic syndrome correlates with an elevation in serum uric
acid as well as a marked increase in total fructose intake (in the form of table sugar and high …

The increasing incidence of obesity and the metabolic syndrome over the past two decades
has coincided with a marked increase in total fructose intake. Fructose—unlike other sugars …

Fructose is a commonly used sweetener associated with diets that increase the prevalence
of metabolic syndrome. Thiazide diuretics are frequently used in these patients for treatment …

Background: Excessive fructose intake causes metabolic syndrome in animals and can be
partially prevented by lowering the uric acid level. We tested the hypothesis that fructose …

Fructose consumption has been recently related to an epidemic of metabolic syndrome, and
hyperuricemia plays a pathogenic role in fructose-induced metabolic syndrome. Fructose …

Metabolic syndrome, characterized by truncal obesity, hypertriglyceridemia, elevated BP,
and insulin resistance, is recognized increasingly as a major risk factor for kidney disease …

There is a direct relationship between fructose intake and serum levels of uric acid (UA),
which is the final product of purine metabolism. Recent preclinical and clinical evidence …

Elevated serum uric acid concentration is a common laboratory finding in subjects with
metabolic syndrome/obesity, hypertension, kidney disease and cardiovascular events …

Increased fructose consumption is associated with hyperuricemia, metabolic syndrome, and
renal damage. This study evaluated whether febuxostat (Fx), an investigational nonpurine …

We propose that excessive fructose intake (> 50 g/d) may be one of the underlying etiologies
of metabolic syndrome and type 2 diabetes. The primary sources of fructose are sugar …