Abstract Background PIVKA-II (DCP) is increasingly used for the diagnosis and the
surveillance of hepatocellular carcinoma (HCC) in at-risk populations. However, to date, few …

Abstract Background Prothrombin/Protein Induced by Vitamin K Absence-II (PIVKA-II) is a
candidate biomarker of hepatocellular cancer, recommended both for diagnostics and …

Abstract Background and Aims Prothrombin induced by vitamin K absence‐II (PIVKA‐II) is a
serum biomarker linked to hepatocellular carcinoma (HCC), showing superiority to alpha …

Background Protein induced by vitamin K absence or antagonist-II (PIVKA-II) has been
widely used as a biomarker for liver cancer diagnosis in Japan for decades. However, the …

Simple Summary The use of tumor biomarkers, although debated, for the surveillance of
patients at risk of HCC, is common practice in many clinical centers. Here, we investigated …

Results This kit has made it possible to detect low concentrations of PIVKA-II in the NC. The
serum PIVKA-II concentration (mean+/-SE) was 15.7+/-1.1 mAu/ml, 16.1+/-2.0 mAu/ml …

Protein induced by vitamin K absence or antagonist-II (PIVKA-II), an abnormal form of
prothrombin, is used as a serological biomarker that aids in the diagnosis of hepatocellular …

Background The concentration of Des-gamma-carboxy-prothrombin (DCP) or PIVKA-II has
been described to be increased in patients with hepatocellular cancer, along with its …

Background Hepatocellular carcinoma (HCC) is one of the most common malignant tumors
of the digestive system and has high morbidity and mortality rates. It is essential to search …

We measured des-γ-carboxyprothrombin (DCP)(prothrombin induced by vitamin K absence
or antagonist-II, abbreviated as PIVKA-II) by a newly developed enzyme immunoassay using …