Background During the final stages of differentiation of mammalian erythroid cells, the
chromatin is condensed and enucleated. We previously reported that Rac GTPases and …

Mammalian erythroid cells undergo enucleation, an asymmetric cell division involving
extrusion of a pycnotic nucleus enveloped by the plasma membrane,,. The mechanisms that …

Terminal erythroid differentiation in vertebrates is characterized by progressive
heterochromatin formation and chromatin condensation and, in mammals, culminates in …

A unique feature in mammalian erythropoiesis is the dramatic chromatin condensation
followed by enucleation. This step-by-step process starts at the beginning of terminal …

Chromatin remodelling in the fertilised mouse egg is intimately linked to protein synthesis
and degradation, to protamine by histone replacement and to specific histone modifications …

In all vertebrates, the cell nucleus becomes highly condensed and transcriptionally inactive
during the final stages of red cell biogenesis. Enucleation, the process by which the nucleus …

Histone deacetylases (HDACs) are a group of enzymes that catalyze the removal of acetyl
groups from histone and nonhistone proteins. HDACs have been shown to have diverse …

Mammalian erythropoiesis involves chromatin condensation that is initiated in the early
stage of terminal differentiation. The mechanisms of chromatin condensation during …

Mammalian terminal erythropoiesis involves gradual but dramatic chromatin condensation
steps that are essential for cell differentiation. Chromatin and nuclear condensation is …

Histone deacetylases (HDACs) are globally implicated in the growth and differentiation of
mammalian cells; however, relatively little is known about their specific roles in …