[HTML][HTML] Dose modification in biologic therapy for moderate to severe psoriasis: a descriptive analysis in a clinical practice setting

O Baniandrés, VJ Rodriguez-Soria… - Actas Dermo …, 2015 - Elsevier
Introduction In biologic therapy, dose modification in carefully selected patients when
psoriasis is in remission could reduce treatment costs and the risks associated with drug …

[HTML][HTML] Evaluation of a one-step dose reduction strategy of adalimumab, etanercept and ustekinumab in patients with psoriasis in daily practice

S Atalay, LS van der Schoot… - Acta dermato …, 2021 - ncbi.nlm.nih.gov
Dose reduction of biologics for psoriasis could contribute to lower drug exposure. This study
evaluated a one-step, tightly controlled, biologic dose reduction strategy in a prospective …

Use of off-label doses is frequent in biologic therapy for moderate to severe psoriasis: a cross-sectional study in clinical practice

JM Carrascosa, I Garcia-Doval… - Journal of …, 2015 - Taylor & Francis
Introduction: Biologic medications increase dramatically the burden of a chronic and high
prevalent disease like psoriasis. The objective of the study was to quantify the use of dose …

Dose adjustment of biologic therapies for psoriasis in dermatological practice: a retrospective study

M Esposito, P Gisondi, A Conti, A Giunta… - Journal of the …, 2017 - Wiley Online Library
Introduction Despite the large routine use of biologic drugs in psoriasis treatment, the
majority of studies do not take into consideration dose‐adjustment practice in 'real …

[HTML][HTML] Patients' perspectives towards biologic dose reduction in psoriasis: a qualitative study

LS van der Schoot, LM Verhoef, I van Ee… - Archives of …, 2023 - Springer
Dose reduction of biologics for psoriasis could contribute to more efficient use of these
expensive medicines. Evidence on opinions of patients with psoriasis regarding dose …

[HTML][HTML] Dose adjustment of biologic treatments for moderate-to-severe plaque psoriasis in the real world: a systematic review

A Gambardella, G Licata, A Sohrt - Dermatology and Therapy, 2021 - Springer
Introduction Dose escalation and reduction of biologic treatments are frequent in clinical
practice. The aim of this systematic review is to summarise evidence on dose adjustment of …

[HTML][HTML] Treatment of moderate to severe plaque psoriasis with biologics: analysis of the additional cost of temporary dose escalation vs switch to another biologic after …

L Puig - Actas Dermo-Sifiliográficas (English Edition), 2014 - Elsevier
Introduction In the event of failure of maintenance therapy with biologic agents for moderate
to severe plaque psoriasis, the possible approaches are to switch to another agent or …

[HTML][HTML] Tight controlled dose reduction of biologics in psoriasis patients with low disease activity: a randomized pragmatic non-inferiority trial

S Atalay, JMPA van den Reek, LJ van Vugt, ME Otero… - BMC dermatology, 2017 - Springer
Background Psoriasis is an immune-mediated chronic inflammatory skin disorder for which
several targeted biologic therapies became available in the last 10 years. Data from patients …

Two-year follow-up of a dose reduction strategy trial of biologics adalimumab, etanercept, and ustekinumab in psoriasis patients in daily practice

S Atalay, J van den Reek… - Journal of …, 2022 - Taylor & Francis
Background/objectives Tightly-controlled dose reduction was possible during 1 year in
psoriasis patients on adalimumab, etanercept or ustekinumab with low disease activity …

Patterns of biologic therapy use in the management of psoriasis: cohort study from the British Association of Dermatologists Biologic Interventions Register (BADBIR)

IYK Iskandar, DM Ashcroft, RB Warren… - British Journal of …, 2017 - academic.oup.com
Background Treatment modifications, including dose escalations, dose reductions, switches,
discontinuations and restarts of biologics may be necessary in the management of psoriasis …