Understanding latent tuberculosis: a moving target
PL Lin, JAL Flynn - The Journal of Immunology, 2010 - journals.aai.org
Tuberculosis (TB) remains a threat to the health of people worldwide. Infection with
Mycobacterium tuberculosis can result in active TB or, more commonly, latent infection …
Mycobacterium tuberculosis can result in active TB or, more commonly, latent infection …
Mycobacterium tuberculosis: immune evasion, latency and reactivation
One-third of the global human population harbours Mycobacterium tuberculosis in dormant
form. This dormant or latent infection presents a major challenge for global efforts to …
form. This dormant or latent infection presents a major challenge for global efforts to …
The spectrum of latent tuberculosis: rethinking the biology and intervention strategies
Immunological tests provide evidence of latent tuberculosis in one third of the global
population, which corresponds to more than two billion individuals. Latent tuberculosis is …
population, which corresponds to more than two billion individuals. Latent tuberculosis is …
Tuberculosis: latency and reactivation
JAL Flynn, J Chan - Infection and immunity, 2001 - Am Soc Microbiol
Tuberculosis is a major cause of death around the world, with most of the 1.5 million deaths
per year attributable to the disease occurring in developing countries. This disease is …
per year attributable to the disease occurring in developing countries. This disease is …
Tuberculosis: an infection-initiated autoimmune disease?
Tuberculosis (TB) is caused by Mycobacterium tuberculosis (Mtb) and provided original
proof that an infectious agent can cause human disease. However, key steps in TB …
proof that an infectious agent can cause human disease. However, key steps in TB …
The end of the binary era: revisiting the spectrum of tuberculosis
PL Lin, JAL Flynn - The Journal of Immunology, 2018 - journals.aai.org
Human Mycobacterium tuberculosis infection was thought to result in either active
symptomatic tuberculosis (TB) or latent asymptomatic infection. It is now clear that this binary …
symptomatic tuberculosis (TB) or latent asymptomatic infection. It is now clear that this binary …
Latent tuberculosis: what the host “sees”?
Mycobacterium tuberculosis (MTB), the causative agent of tuberculosis (TB), is the most
successful pathogen of mankind and remains a major threat to global health as the leading …
successful pathogen of mankind and remains a major threat to global health as the leading …
Diagnosis and management of latent tuberculosis infection
L Muñoz, HR Stagg, I Abubakar - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
The post-2015 World Health Organization global tuberculosis strategy recognizes that
elimination requires a focus on reducing the pool of latently infected individuals, an …
elimination requires a focus on reducing the pool of latently infected individuals, an …
Human immunology of tuberculosis
Immunology is a central theme when it comes to tuberculosis (TB). The outcome of human
infection with Mycobacterium tuberculosis is dependent on the ability of the immune …
infection with Mycobacterium tuberculosis is dependent on the ability of the immune …
[HTML][HTML] The knowns and unknowns of latent Mycobacterium tuberculosis infection
WH Boom, UE Schaible… - The Journal of clinical …, 2021 - Am Soc Clin Investig
Humans have been infected with Mycobacterium tuberculosis (Mtb) for thousands of years.
While tuberculosis (TB), one of the deadliest infectious diseases, is caused by uncontrolled …
While tuberculosis (TB), one of the deadliest infectious diseases, is caused by uncontrolled …