Podophyllotoxin (PPT) has attracted researchers' attention because of its ability to treat
various ailments. A series of podophyllotoxin derivatives (PPTs) have been synthesized as …

Podophyllotoxin (PTOX) is a biologically active compound derived from the podophyllum
plant, and both it and its derivatives possess excellent antitumor activity. The PTOX …

Cancer is one of the leading groups of threatened caused by abnormal state cell growth and
second leading diseases involved in the major global death. To treat this, research looking …

Podophyllotoxins, including epipodophyllotoxin derivatives, can act on a diverse array of
drug targets in cancer cells and thus possess potent activity against various forms of cancer …

Podophyllotoxin (PPT) has shown strong antitumor effects on various types of cancers.
However, the non-specific toxicity and poor solubility severely limits its clinical …

Podophyllotoxin (PPT), an aryltetralin-type lignan isolated from Podophyllum species,
exhibits a wide range of biologic and pharmacologic activities, and mainly serves as an …

Podophyllotoxin (PPT), as well as its congeners and derivatives, exhibits pronounced
biological activities, especially antineoplastic effects. Its strong inhibitory effect on tumor cell …

Covering: up to 2020 As a main bioactive component of the Chinese, Indian, and American
Podophyllum species, the herbal medicine, podophyllotoxin (PTOX) exhibits broad spectrum …

Podophyllotoxin (PPT) has been reported to have many pharmacological activities,
especially its anti-tumor effects. To improve the cytotoxicity and selective effect of PPT, in this …

Podophyllotoxins and epipodophyllotoxins, possess excellent activity against both drug-
sensitive and drug-resistant even multidrug-resistant cancer cells via inhibition of tubulin …