Background: Approximately 200,000 people undergo a lower extremity amputation each
year. Following amputation, patients suffer from chronic pain, inability to ambulate, and high …

The life altering nature of major limb amputations may be further complicated by neuroma
formation in up to 60% of the estimated 2 million major limb amputees in the United States …

Background: It is estimated that by 2050, a total of 3.6 million patients will be living with an
amputation in the United States. The objective of this systematic review is to evaluate the …

Background Targeted muscle reinnervation is an emerging surgical technique to treat
neuroma pain whereby sensory and mixed motor nerves are transferred to nearby …

Scope and Significance: There are∼ 185,000 amputations each year and nearly 2 million
amputees currently living in the United States. Approximately 25% of these amputees will …

Background: Orthopaedic trauma etiologies are a common cause for amputation. Targeted
muscle reinnervation (TMR) is a technique aimed at reducing or preventing pain and …

Background: Targeted muscle reinnervation (TMR) and regenerative peripheral nerve
interface (RPNI) procedures have been shown to improve patient-reported outcomes for the …

Background Secondary to vascular disease, oncological resection, or devastating trauma,
lower extremity amputations are performed globally at a yearly rate exceeding 1 million …

Background A majority of the nearly 2 million Americans living with limb loss suffer from
chronic pain in the form of neuroma-related residual limb and phantom limb pain (PLP) …

Objective: To compare targeted muscle reinnervation (TMR) to “standard treatment” of
neuroma excision and burying into muscle for postamputation pain. Summary Background …