It is well known that regular exercise can benefit health by enhancing antioxidant defenses
in the body. However, unaccustomed and/or exhaustive exercise can generate excessive …

A large number of researches have led to a substantial growth of knowledge about exercise
and oxidative stress. Initial investigations reported that physical exercise generates free …

In this review, we discuss exercise as an oxidative stressor, and elucidate the mechanisms
and downstream consequences of exercise-induced oxidative stress. Reactive oxygen …

The first report demonstrating that prolonged endurance exercise promotes oxidative stress
in humans was published more than 4 decades ago. Since this discovery, many ensuing …

Physical exercise represents a major challenge to whole-body homeostasis, provoking
acute and adaptative responses at the cellular and systemic levels. Different sources of …

Although regular muscular exercise is known to have many beneficial effects, exercise
results in an increased production of radicals and other forms of reactive oxygen species …

Unaccustomed and/or exhaustive exercise generates excessive free radicals and reactive
oxygen and nitrogen species leading to muscle oxidative stress-related damage and …

Recent research highlights the importance of redox signalling pathway activation by
contraction-induced reactive oxygen species (ROS) and nitric oxide (NO) in normal exercise …

Significance: Exercise-induced reactive oxygen species (ROS) production activates multiple
intracellular signaling pathways through genomic and nongenomic mechanisms that are …

It is well established that the increase in reactive oxygen species (ROS) and free radicals
production during exercise has both positive and negative physiological effects. Among …