In the last decade, we witnessed discoveries that established Zn2+ as a second major
signalling metal ion in the transmission of information within cells and in communication …

Homeostatic control maintains essential transition metal ions at characteristic cellular
concentrations to support their physiological functions and to avoid adverse effects. Zinc is …

Chapters in this book review the remarkable advances in the field of zinc biology over the
last decade. Zinc is essential for life, in particular for growth and development, through its …

The essential trace element zinc (Zn) is widely required in cellular functions, and abnormal
Zn homeostasis causes a variety of health problems that include growth retardation …

Zinc (II) ions are essential for all forms of life. In humans, they have catalytic and structural
functions in an estimated 3,000 zinc proteins. In addition, they interact with proteins …

The vast knowledge of the physiologic functions of zinc in at least 3000 proteins and the
recent recognition of fundamental regulatory functions of zinc (II) ions released from cells or …

Abstract Zinc (Zn 2+) is an essential micronutrient that is required for a wide variety of
cellular processes. Tools and methods have been instrumental in revealing the myriad roles …

Zinc metabolism at the cellular level is critical for many biological processes in the body. A
key observation is the disruption of cellular homeostasis, often coinciding with disease …

The nutritional essentiality of zinc for the growth of living organisms had been recognized
long before zinc biochemistry began with the discovery of zinc in carbonic anhydrase in …

Zinc is an essential trace element for life. Zinc is not only an important nutrient, cofactor of
numerous enzymes and transcription factors, but also it acts as an intracellular mediator …