Aging-induced structural and functional alterations of the neurovascular unit lead to
impairment of neurovascular coupling responses, dysregulation of cerebral blood flow, and …

Adjustment of cerebral blood flow (CBF) to neuronal activity via neurovascular coupling
(NVC) has an essential role in maintenance of healthy cognitive function. In aging increased …

Age-related impairment of angiogenesis likely has a critical role in cerebromicrovascular
rarefaction and development of vascular cognitive impairment and dementia (VCID) in the …

Adjustment of cerebral blood flow (CBF) to neuronal activity via neurovascular coupling
(NVC) plays an important role in the maintenance of healthy cognitive function. Strong …

We tested the hypothesis that supplementation of nicotinamide mononucleotide (NMN), a
key NAD+ intermediate, increases arterial SIRT 1 activity and reverses age‐associated …

Understanding molecular mechanisms involved in vascular aging is essential to develop
novel interventional strategies for treatment and prevention of age-related vascular …

Moment-to-moment adjustment of cerebral blood flow (CBF) to neuronal activity via the
homeostatic mechanism known as neurovascular coupling (NVC) has an essential role in …

Background Microglial-mediated neuroinflammation plays an important role in vascular
dementia, and modulating neuroinflammation has emerged as a promising treatment target …

NAD+ availability decreases with age and in certain disease conditions. Nicotinamide
mononucleotide (NMN), a key NAD+ intermediate, has been shown to enhance NAD+ …

Moment‐to‐moment adjustment of cerebral blood flow (CBF) via neurovascular coupling
has an essential role in maintenance of healthy cognitive function. In advanced age …