Therapeutic effect of human amniotic membrane–derived cells on experimental arthritis and other inflammatory disorders

O Parolini, L Souza‐Moreira, F O'Valle… - Arthritis & …, 2014 - Wiley Online Library
Objective Rheumatoid arthritis (RA) is an autoimmune disease caused by loss of
immunologic self tolerance and characterized by chronic joint inflammation. Cells isolated …

[PDF][PDF] Transplantation of human amnion mesenchymal cells attenuates the disease development in rats with collagen-induced arthritis

J Shu, L Pan, X Huang, P Wang, H Li… - Clin Exp …, 2015 - clinexprheumatol.org
Objective Human amnion mesenchymal cells (hAMCs), isolated from the amniotic
membrane of human placenta, are a unique population of mesenchymal stem cells (MSCs) …

Transforming growth factor β–transduced mesenchymal stem cells ameliorate experimental autoimmune arthritis through reciprocal regulation of Treg/Th17 cells and …

MJ Park, HS Park, ML Cho, HJ Oh, YG Cho… - Arthritis & …, 2011 - Wiley Online Library
Objective Bone marrow–derived mesenchymal stem cells (MSCs) can prevent various
autoimmune diseases. We examined the therapeutic potential of transforming growth factor …

Human embryonic stem cell-derived mesenchymal stromal cells ameliorate collagen-induced arthritis by inducing host-derived indoleamine 2, 3 dioxygenase

E Gonzalo-Gil, MJ Pérez-Lorenzo, M Galindo… - Arthritis research & …, 2016 - Springer
Background The immunosuppressive and anti-inflammatory properties of mesenchymal
stromal cells (MSC) have prompted their therapeutic application in several autoimmune …

Treatment of experimental arthritis by inducing immune tolerance with human adipose‐derived mesenchymal stem cells

MA González, E Gonzalez‐Rey, L Rico… - … : Official Journal of …, 2009 - Wiley Online Library
Objective Rheumatoid arthritis (RA) is a chronic autoimmune disease caused by loss of
immunologic self tolerance and characterized by chronic joint inflammation. Adult …

Enhanced immunoregulation of mesenchymal stem cells by IL-10-producing type 1 regulatory T cells in collagen-induced arthritis

JY Lim, KI Im, ES Lee, N Kim, YS Nam, YW Jeon… - Scientific Reports, 2016 - nature.com
Mesenchymal stem cells (MSCs) possess immunomodulatory properties and have potential,
however, there have been conflicting reports regarding their effects in rheumatoid arthritis …

Immunomodulatory properties of mesenchymal stem cell in experimental arthritis in rat and mouse models: A systematic review

K Hynes, R Bright, S Proudman, D Haynes… - Seminars in Arthritis and …, 2016 - Elsevier
Background Despite recent advances in the treatment of arthritis with the development of
disease-modifying antirheumatic drugs, 30% of patients still fail to respond to treatment …

Adoptive transfer of human gingiva‐derived mesenchymal stem cells ameliorates collagen‐induced arthritis via suppression of Th1 and Th17 cells and enhancement …

M Chen, W Su, X Lin, Z Guo, J Wang… - Arthritis & …, 2013 - Wiley Online Library
Objective Current approaches offer no cures for rheumatoid arthritis (RA). Accumulating
evidence has revealed that manipulation of bone marrow–derived mesenchymal stem cells …

Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis

Y Liu, R Mu, S Wang, L Long, X Liu, R Li, J Sun… - Arthritis research & …, 2010 - Springer
Introduction Rheumatoid arthritis (RA) is a T-cell-mediated systemic autoimmune disease,
characterized by synovium inflammation and articular destruction. Bone marrow …

Discrepancy between the in vitro and in vivoeffects of murine mesenchymal stem cells on T-cell proliferation and collagen-induced arthritis

E Schurgers, H Kelchtermans, T Mitera… - Arthritis research & …, 2010 - Springer
Introduction The goal of this study is to analyze the potential immunosuppressive properties
of mesenchymal stem cells (MSC) on T cell proliferation and in collagen-induced arthritis …