Significant heterogeneity of clinical presentation and disease progression exists within
chronic obstructive pulmonary disease (COPD). Although FEV1 inadequately describes this …

Abstract Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous and
multisystemic disease with progressive increasing morbidity and mortality. COPD is now …

The current clinical classification of smoking-related lung disease fails to take into account
the heterogeneity of chronic obstructive pulmonary disease (COPD). With an increased …

Update on Clinical Aspects of Chronic Obstructive Pulmonary Disease | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Clinical phenotyping is currently used to guide pharmacological treatment decisions in
chronic obstructive pulmonary disease (COPD), a personalized approach to care. Precision …

Chronic obstructive pulmonary disease (COPD) has been a major public health problem
during the 20th century, and will remain a challenge for the foreseeable future. Worldwide …

Update on the Pathogenesis of Chronic Obstructive Pulmonary Disease | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Chronic obstructive pulmonary disease is a varied condition when examined from a number
of different perspectives including factors which influence disease development …

Summary⇓ Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity
and mortality in the USA, and it remains one of the few diseases that continues to increase …

Background The traditional classification of COPD, which relies solely on spirometry, fails to
account for the complexity and heterogeneity of the disease. Phenotyping is a method that …