Muscle fiber type diversification during exercise and regeneration

R Qaisar, S Bhaskaran, H Van Remmen - Free Radical Biology and …, 2016 - Elsevier
The plasticity of skeletal muscle can be traced down to extensive metabolic, structural and
molecular remodeling at the single fiber level. Skeletal muscle is comprised of different fiber …

[HTML][HTML] Redox signaling regulates skeletal muscle remodeling in response to exercise and prolonged inactivity

SK Powers, M Schrager - Redox biology, 2022 - Elsevier
Skeletal muscle fibers are malleable and undergo rapid remodeling in response to
increased contractile activity (ie, exercise) or prolonged periods of muscle inactivity (eg …

Exercise-induced skeletal muscle signaling pathways and human athletic performance

DM Camera, WJ Smiles, JA Hawley - Free Radical Biology and Medicine, 2016 - Elsevier
Skeletal muscle is a highly malleable tissue capable of altering its phenotype in response to
external stimuli including exercise. This response is determined by the mode,(endurance …

[PDF][PDF] Mechanisms modulating skeletal muscle phenotype

B Blaauw, S Schiaffino, C Reggiani - Compr Physiol, 2013 - researchgate.net
Mammalian skeletal muscles are composed of a variety of highly specialized fibers whose
selective recruitment allows muscles to fulfill their diverse functional tasks. In addition …

Reactive oxygen species are signalling molecules for skeletal muscle adaptation

SK Powers, J Duarte, AN Kavazis… - Experimental …, 2010 - Wiley Online Library
Increased reactive oxygen species (ROS) production is crucial to the remodelling that occurs
in skeletal muscle in response to both exercise training and prolonged periods of disuse …

Reactive oxygen and nitrogen species as intracellular signals in skeletal muscle

SK Powers, EE Talbert… - The Journal of physiology, 2011 - Wiley Online Library
It is well established that contracting skeletal muscles produce free radicals. Given that
radicals are known to play a prominent role in the pathogenesis of several diseases, the …

Regulation of exercise-induced fiber type transformation, mitochondrial biogenesis, and angiogenesis in skeletal muscle

Z Yan, M Okutsu, YN Akhtar… - Journal of applied …, 2011 - journals.physiology.org
Skeletal muscle exhibits superb plasticity in response to changes in functional demands.
Chronic increases of skeletal muscle contractile activity, such as endurance exercise, lead to …

Signaling pathways in skeletal muscle remodeling

R Bassel-Duby, EN Olson - Annu. Rev. Biochem., 2006 - annualreviews.org
Skeletal muscle is comprised of heterogeneous muscle fibers that differ in their physiological
and metabolic parameters. It is this diversity that enables different muscle groups to provide …

Functional, structural and molecular plasticity of mammalian skeletal muscle in response to exercise stimuli

M Flück - Journal of Experimental Biology, 2006 - journals.biologists.com
Biological systems have acquired effective adaptive strategies to cope with physiological
challenges and to maximize biochemical processes under imposed constraints. Striated …

Activity-dependent signaling pathways controlling muscle diversity and plasticity

S Schiaffino, M Sandri, M Murgia - Physiology, 2007 - journals.physiology.org
A variety of fiber types with different contractile and metabolic properties is present in
mammalian skeletal muscle. The fiber-type profile is controlled by nerve activity via specific …