Migraines constitute a common neurological and headache disorder affecting around 15%
of the world's population. In addition to other mechanisms, neurogenic neuroinflammation …

Migraine is a prevalent disorder, affecting 15.1% of the world's population. In most cases, the
migraine attacks are sporadic; however, some individuals experience a gradual increase in …

Migraine is a primary headache disorder characterized by a unilateral, throbbing, pulsing
headache, which lasts for hours to days, and the pain can interfere with daily activities. It …

Background Pain is generally concomitant with an inflammatory reaction at the site where
the nociceptive fibers are activated. Rodent studies suggest that a sterile meningeal …

Migraine is a severe and debilitating disorder of the brain that involves a constellation of
neurological symptoms alongside head pain. Its pathophysiology is only beginning to be …

The implications of neurogenic inflammation and neuroinflammation in the pathophysiology
of migraine have been clearly demonstrated in preclinical migraine models involving several …

The role of neuroinflammation in the pathophysiology of migraines is increasingly being
recognized, and cytokines, which are important endogenous substances involved in …

Migraine is a neurovascular disorder that induces debilitating headaches associated with
multiple symptoms including facial allodynia, characterized by heightened responsivity to …

Background The exact mechanisms underlying the onset of a migraine attack are not
completely understood. It is, however, now well accepted that the onset of the excruciating …

Background Migraine is a complex, chronic, painful, neurovascular disorder characterized
by episodic activation of the trigeminal system. Increased levels of calcitonin gene-related …