EVOO's Effects on Incretin Production: Is There a Rationale for a Combination in T2DM Therapy?

S Amodeo, L Mirarchi, A Seidita, R Citarrella… - International Journal of …, 2022 - mdpi.com
Type 2 diabetes mellitus (T2DM) is a serious public health concern as it is one of the most
common chronic diseases worldwide due to social and economic developments that have …

Comparing olive oil and C4-dietary oil, a prodrug for the GPR119 agonist, 2-oleoyl glycerol, less energy intake of the latter is needed to stimulate incretin hormone …

MJ Mandøe, KB Hansen, JA Windeløv, FK Knop… - Nutrition & …, 2018 - nature.com
Background/objective After digestion, dietary triacylglycerol stimulates incretin release in
humans, mainly through generation of 2-monoacylglycerol, an agonist for the intestinal G …

The Mediterranean diet increases glucagon‐like peptide 1 and oxyntomodulin compared with a vegetarian diet in patients with type 2 diabetes: A randomized …

A Di Mauro, D Tuccinardi, M Watanabe… - Diabetes/metabolism …, 2021 - Wiley Online Library
Abstract Aim To compare a Mediterranean diet (MED) with a high‐fibre vegetarian diet
(HFV) in terms of hunger‐satiety perception through post‐prandial assessment of appetite …

The incretin pathway as a new therapeutic target for obesity

TM Barber, H Begbie, J Levy - Maturitas, 2010 - Elsevier
The global obesity epidemic fuelled by our obesogenic environment, and the prevention and
treatment of obesity are some of the most important health-care challenges of our time …

Update on incretin hormones

LK Phillips, JB Prins - Annals of the New York Academy of …, 2011 - Wiley Online Library
The incretin hormones glucagon‐like‐peptide‐1 (GLP‐1) and glucose‐dependent
insulinotropic polypeptide (GIP) are released from the intestine following oral ingestion of …

Incretin hormones and type 2 diabetes—mechanistic insights and therapeutic approaches

GA Boer, JJ Holst - Biology, 2020 - mdpi.com
Simple Summary When we ingest a meal, our intestine secretes hormones that are released
into the bloodstream. Amongst these hormones are the incretins hormones which stimulate …

Role and mechanism (s) of incretin-dependent therapies for treating diabetes mellitus

NE Nasr, KM Sadek - Environmental Science and Pollution Research, 2022 - Springer
Diabetes mellitus (DM) is a worldwide ailment which leads to chronic complications like
cardiac disorders, renal perturbations, limb amputation and blindness. Type one diabetes …

Defining the role of GLP-1 in the enteroinsulinar axis in type 2 diabetes using DPP-4 inhibition and GLP-1 receptor blockade

BA Aulinger, A Bedorf, G Kutscherauer, J de Heer… - Diabetes, 2014 - Am Diabetes Assoc
Understanding the incretin pathway has led to significant advancements in the treatment of
type 2 diabetes (T2D). Still, the exact mechanisms are not fully understood. In a randomized …

The role of incretins in glucose homeostasis and diabetes treatment

W Kim, JM Egan - Pharmacological reviews, 2008 - ASPET
Incretins are gut hormones that are secreted from enteroendocrine cells into the blood within
minutes after eating. One of their many physiological roles is to regulate the amount of …

[PDF][PDF] Nutrient-mediated modulation of incretin gene expression: a systematic review

R Martínez-Rodríguez, A Gil - Nutr Hosp, 2012 - nutricionhospitalaria.com
Incretins are a cluster of hormones which are secreted and released into the bloodstream
after food intake by gut enteroendocrine cells, reaching to pancreas where produce a …