Melanotransferrin induces human melanoma SK-Mel-28 cell invasion in vivo

Y Bertrand, M Demeule, J Michaud-Levesque… - Biochemical and …, 2007 - Elsevier
The expression of melanotransferrin (MTf), a membrane-bound glycoprotein highly
expressed in melanomas, is correlated with tumor vascularization and progression …

The function of melanotransferrin: a role in melanoma cell proliferation and tumorigenesis

LL Dunn, EO Sekyere, Y Suryo Rahmanto… - …, 2006 - academic.oup.com
Melanotransferrin (MTf) or melanoma tumor antigen p97 is an iron (Fe) binding transferrin
homolog expressed highly on melanomas and at lower levels on normal tissues. It has been …

Stimulation of cell surface plasminogen activation by membrane-bound melanotransferrin: a key phenomenon for cell invasion

J Michaud-Levesque, M Demeule, R Béliveau - Experimental cell research, 2005 - Elsevier
The activation of plasminogen at the cell surface is a crucial step in cell migration and
invasion. In the present study, the effect of membrane-bound melanotransferrin (mMTf), also …

In vivo inhibition of angiogenesis by a soluble form of melanotransferrin

J Michaud-Levesque, M Demeule, R Béliveau - Carcinogenesis, 2007 - academic.oup.com
Abstract Melanotransferrin (MTf), the membrane-bound human melanoma antigen p97,
binds to plasminogen and stimulates its activation, thus regulating a crucial step involved in …

Inhibition of tumor growth by a truncated and soluble form of melanotransferrin

Y Rolland, M Demeule, J Michaud-Levesque… - Experimental cell …, 2007 - Elsevier
Melanotransferrin is a glycoprotein expressed at the cell membrane and secreted in the
extracellular environment. Recombinant truncated form of membrane-bound …

Inhibition of melanoma brain metastasis by targeting melanotransferrin at the cell surface

Y Rolland, M Demeule, L Fenart… - Pigment cell & …, 2009 - Wiley Online Library
Brain metastases are a common feature of malignant melanoma and are associated with
poor prognosis. Melanotransferrin (MTf), one of several antigens associated with the surface …

Identification of distinct changes in gene expression after modulation of melanoma tumor antigen p97 (melanotransferrin) in multiple models in vitro and in vivo

Y Suryo Rahmanto, LL Dunn, DR Richardson - Carcinogenesis, 2007 - academic.oup.com
Melanoma tumor antigen p97 or melanotransferrin (MTf) is an iron (Fe)-binding protein with
high homology to serum transferrin. MTf is expressed at very low levels in normal tissues …

The human melanoma associated protein melanotransferrin promotes endothelial cell migration and angiogenesis in vivo

R Sala, WA Jefferies, B Walker, J Yang, J Tiong… - European journal of cell …, 2002 - Elsevier
Melanotransferrin is a member of the transferrin family, which is comprised of serum
transferrin, lactoferrin and ovotransferrin, and is highly expressed on melanoma cells …

The membrane-bound and soluble form of melanotransferrin function independently in the diagnosis and targeted therapy of lung cancer

Y Lei, Z Lu, J Huang, R Zang, Y Che, S Mao… - Cell Death & …, 2020 - nature.com
Melanotransferrin (MFI2) is a newly identified tumor-associated protein, which consists of
two forms of proteins, membrane-bound (mMFI2) and secretory (sMFI2). However, little is …

[HTML][HTML] Generation and characterization of transgenic mice hyper-expressing melanoma tumour antigen p97 (Melanotransferrin): no overt alteration in phenotype

YS Rahmanto, DR Richardson - … et Biophysica Acta (BBA)-Molecular Cell …, 2009 - Elsevier
Melanotransferrin (MTf) is a transferrin homologue that binds iron (Fe) through a high affinity
Fe-binding site. MTf has been implicated in diverse processes, eg, iron metabolism …