Efficacy and safety of spesolimab for the management of generalized pustular psoriasis: a drug safety evaluation
L Potestio, E Camela, S Cacciapuoti… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Generalized pustular psoriasis (GPP) is a rare form of psoriasis (less of 1% of
cases). Currently, GPP is recognized as a clinical entity, distinguished from plaque psoriasis …
cases). Currently, GPP is recognized as a clinical entity, distinguished from plaque psoriasis …
Therapeutic Potential of Spesolimab-Sbzo in the Management of Generalized Pustular Psoriasis Flares in Adults: Evidence to Date
F Rega, F Trovato, G Bortone, G Pellacani… - … : Targets and Therapy, 2024 - Taylor & Francis
Generalized pustular psoriasis (GPP) is a rare, chronic, and severe skin disorder
characterized by the eruption of non-infectious pustules on an erythematous background …
characterized by the eruption of non-infectious pustules on an erythematous background …
[HTML][HTML] Design of Effisayil™ 2: a randomized, double-blind, placebo-controlled study of spesolimab in preventing flares in patients with generalized pustular psoriasis
Introduction Generalized pustular psoriasis (GPP) is a rare autoinflammatory skin disease
characterized by flares of widespread erythema with sterile pustules, and can be relapsing …
characterized by flares of widespread erythema with sterile pustules, and can be relapsing …
Efficacy of spesolimab for the treatment of generalized pustular psoriasis flares across pre‐specified patient subgroups in the Effisayil 1 study
AD Burden, Y Okubo, M Zheng, D Thaçi… - Experimental …, 2023 - Wiley Online Library
Effisayil 1 was a multicentre, randomized, double‐blind, placebo‐controlled study of the anti‐
interleukin (IL)‐36 receptor monoclonal antibody, spesolimab, in patients presenting with a …
interleukin (IL)‐36 receptor monoclonal antibody, spesolimab, in patients presenting with a …
[HTML][HTML] Spesolimab for the treatment of generalized pustular psoriasis
D Bernardo, D Thaçi, T Torres - Drugs, 2024 - Springer
Generalized pustular psoriasis (GPP) is a rare but severe skin inflammatory disorder
characterized by the eruption of widespread sterile neutrophilic pustules, often accompanied …
characterized by the eruption of widespread sterile neutrophilic pustules, often accompanied …
Efficacy and safety of spesolimab in Asian patients with a generalized pustular psoriasis flare: Results from the randomized, double‐blind, placebo‐controlled Effisayil …
A Morita, TF Tsai, EYW Yee, Y Okubo… - The Journal of …, 2023 - Wiley Online Library
Generalized pustular psoriasis is a potentially life‐threatening neutrophilic skin disease
characterized by recurrent flares of widespread erythema and eruption of sterile pustules. In …
characterized by recurrent flares of widespread erythema and eruption of sterile pustules. In …
Exploring the clinical assessment, guidelines, and options for the treatment of generalized pustular psoriasis [podcast]
EJ Song, C Liu - Clinical, Cosmetic and Investigational …, 2023 - Taylor & Francis
Acute episodes of generalized pustular psoriasis (GPP), known as “flares”, are characterized
by the widespread appearance of pustules with surrounding skin erythema, and are often …
by the widespread appearance of pustules with surrounding skin erythema, and are often …
Use of biological therapies for the management of pustular psoriasis: a new era?
M Megna, E Camela, A Ruggiero… - Clinical, cosmetic and …, 2023 - Taylor & Francis
Generalized pustular psoriasis (GPP) is a severe and rare form of psoriasis, being a
potentially life-threatening condition, characterized by recurring episodes or flares of …
potentially life-threatening condition, characterized by recurring episodes or flares of …
Spesolimab treatment in a patient with generalized pustular psoriasis: a case report with 12-month follow-up and literature review
JA Cardenas-de la Garza… - Clinical and …, 2024 - academic.oup.com
This article explores the use of spesolimab in generalized pustular psoriasis (GPP) and
presents the case of a Hispanic patient with GPP and plaque psoriasis treated with …
presents the case of a Hispanic patient with GPP and plaque psoriasis treated with …
[HTML][HTML] Trial of spesolimab for generalized pustular psoriasis
H Bachelez, SE Choon, S Marrakchi… - … England Journal of …, 2021 - Mass Medical Soc
Background Generalized pustular psoriasis (GPP) is a rare, life-threatening, inflammatory
skin disease characterized by widespread eruption of sterile pustules. Interleukin-36 …
skin disease characterized by widespread eruption of sterile pustules. Interleukin-36 …
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