Automation and data-driven design of polymer therapeutics
Polymers are uniquely suited for drug delivery and biomaterial applications due to tunable
structural parameters such as length, composition, architecture, and valency. To facilitate …
structural parameters such as length, composition, architecture, and valency. To facilitate …
Applied machine learning as a driver for polymeric biomaterials design
SM McDonald, EK Augustine, Q Lanners… - Nature …, 2023 - nature.com
Polymers are ubiquitous to almost every aspect of modern society and their use in medical
products is similarly pervasive. Despite this, the diversity in commercial polymers used in …
products is similarly pervasive. Despite this, the diversity in commercial polymers used in …
Data-driven design of polymer-based biomaterials: high-throughput simulation, experimentation, and machine learning
Polymers, with the capacity to tunably alter properties and response based on manipulation
of their chemical characteristics, are attractive components in biomaterials. Nevertheless …
of their chemical characteristics, are attractive components in biomaterials. Nevertheless …
Challenges and opportunities of polymer design with machine learning and high throughput experimentation
In this perspective, the authors challenge the status quo of polymer innovation. The authors
first explore how research in polymer design is conducted today, which is both time …
first explore how research in polymer design is conducted today, which is both time …
Data-driven methods for accelerating polymer design
TK Patra - ACS Polymers Au, 2021 - ACS Publications
Optimal design of polymers is a challenging task due to their enormous chemical and
configurational space. Recent advances in computations, machine learning, and increasing …
configurational space. Recent advances in computations, machine learning, and increasing …
Machine learning models to accelerate the design of polymeric long-acting injectables
Long-acting injectables are considered one of the most promising therapeutic strategies for
the treatment of chronic diseases as they can afford improved therapeutic efficacy, safety …
the treatment of chronic diseases as they can afford improved therapeutic efficacy, safety …
Polymers for biomedical applications: The importance of hydrophobicity in directing biological interactions and application efficacy
AK Pearce, RK O'Reilly - Biomacromolecules, 2021 - ACS Publications
The past decades have seen significant research effort in the field of polymers for a range of
biomedical applications, driven by the promising prospect of these materials for realizing …
biomedical applications, driven by the promising prospect of these materials for realizing …
Navigating the Expansive Landscapes of Soft Materials: A User Guide for High-Throughput Workflows
EC Day, SS Chittari, MP Bogen, AS Knight - ACS Polymers Au, 2023 - ACS Publications
Synthetic polymers are highly customizable with tailored structures and functionality, yet this
versatility generates challenges in the design of advanced materials due to the size and …
versatility generates challenges in the design of advanced materials due to the size and …
[图书][B] De novo molecular design
G Schneider - 2013 - books.google.com
Systematically examining current methods and strategies, this ready reference covers a
wide range of molecular structures, from organic-chemical drugs to peptides, Proteins and …
wide range of molecular structures, from organic-chemical drugs to peptides, Proteins and …
Sequence-defined synthetic polymers for new-generation functional biomaterials
Synthetic polymers have been extensively exploited for biomedical and pharmacological
applications, spanning from surgical devices, diagnostics, tissue engineering, regenerative …
applications, spanning from surgical devices, diagnostics, tissue engineering, regenerative …