Background With the exponential growth of publicly available genome sequences,
pangenome analyses have provided increasingly complete pictures of genetic diversity for …

The pan-genome is defined as the combined set of all genes in the gene pool of a species.
Pan-genome analyses have been very useful in helping to understand different evolutionary …

Highlights•Next generation sequencing technologies have enabled large-scale genome
analyses.•Pan-genome analyses provide a framework for predicting and modeling genomic …

The use of comparative genomics for functional, evolutionary, and epidemiological studies
requires methods to classify gene families in terms of occurrence in a given species. These …

An astronomical increase in microbial genome data in recent years has led to strong
demand for bioinformatic tools for pan-genome analysis within and across species. Here, we …

The pangenome refers to a collection of genomic sequence found in the entire species or
population rather than in a single individual; the sequence can be core, present in all …

Highlights•Wealth of genome data are making pan-genome analysis increasingly
possible.•Pan-genome analysis is an effective approach to understand pathogenic …

Background Comparative genomics is a powerful approach for studying variation in
physiological traits as well as the evolution and ecology of microorganisms. Recent …

Microbial organisms inhabit virtually all environments and encompass a vast biological
diversity. The pangenome concept aims to facilitate an understanding of diversity within …

The study of the gene repertoires of microbial species, their pangenomes, has become a key
part of microbial evolution and functional genomics. Yet, the increasing number of genomes …