This review focuses on DNA damage caused by a variety of oxidizing, alkylating, and
nitrating species, and it may play an important role in the pathophysiology of inflammation …

Reactive oxygen and nitrogen species are known to participate in a wide variety of human
diseases. Oxidative DNAdamage is involved in chemical carcinogenesis and aging …

Oxidative damage DNA is an inevitable, natural consequence of cellular metabolism
resulting from formation of reactive oxygen species (ROS) in cluding free oxygen radicals …

A broad scientific community is involved in investigations aimed at delineating the
mechanisms of formation and cellular processing of oxidatively generated damage to …

The oxidation and nitration reactions in DNA associated with the combination of nitrogen
dioxide radicals with 8-oxo-7, 8-dihydroguanine (8-oxoGua) and guanine radicals were …

In this review article, emphasis is placed on the critical survey of available data concerning
modified nucleobase and 2-deoxyribose products that have been identified in cellular DNA …

The authors review studies on 8-nitroguanine (8-NO2-G) formed by reactions of guanine,
guanosine, and 2́-deoxyguanosine, either free or in DNA or RNAwith reactive nitrogen …

A variety of endogenous and exogenous agents can induce DNA damage and lead to
genomic instability. Reactive oxygen species (ROS), an important class of DNA damaging …

The chemistry of DNA and its repair selectivity control the influence of genomic oxidative
stress on the development of serious disorders such as cancer and heart diseases. DNA is …

Purpose One outcome of DNA damage from hydroxyl radical generated by ionizing radiation
(IR) or by the Fenton reaction is oxidation of the nucleobases, especially guanine (G). While …