Expression, Microencapsulation of Recombinant Human Epidermal Growth Factor, and Release Study in Gastric Ulcer Representing Condition

RD Pratiwi, N Yudasari, VA Rosyidi… - Indonesian Journal of …, 2021 - journal.ugm.ac.id
Recombinant human epidermal growth factor (rhEGF) has been studied and expressed in
various expression systems. It has been also commercialized and clinically used, yet limited …

[HTML][HTML] Enhancement of wound healing by topical application of epidermal growth factor in animal model

G Zhu, HL Xu, XP Zhou, QW Zhi - Universal Journal of …, 2020 - ujpronline.com
Objective: Wound healing is a complex process of biological events involving re-
epithelialization and granulation that are mainly mediated by several endogenously …

Chitosan-microencapsulated rhEGF in promoting wound healing

HC Tsai, C Sheng, LS Chang, ZH Wen… - Journal of Wound …, 2021 - magonlinelibrary.com
Aims: Chitosan and epidermal growth factor (EGF) have been shown to improve wound
healing. This study investigates the healing effects of a spray solution (NewEpi, JoyCom Bio …

[HTML][HTML] Cloning, expression, and cost effective purification of authentic human epidermal growth factor with high activity

S Pouranvari, F Ebrahimi, G Javadi… - Iranian Red Crescent …, 2016 - ncbi.nlm.nih.gov
Background: Epidermal growth factor (EGF) plays a fundamental role in the healing of
wounds relating to skin damage, the cornea, and the gastrointestinal tract. Objectives: The …

[PDF][PDF] Oral Bioadhesive Gels of Recombinant Human Epidermal Growth Factor (rhEGF) for the Healing of Gastric Ulcers

K Han, SJ Lee, JH Kim, YB Chung - Journal of Pharmaceutical …, 1998 - koreascience.kr
The objective of this study was to develop effective oral formulations of rhEGF for gastric
ulcer healing using polycarbophil. hydroxypropylcellulose (HPC) and sucralfate as its …

Production of recombinant human epidermal growth factor and assessment of its activity in cell viability

S Pouranvari, F Ebrahimi, G Javadi… - … University of Medical …, 2015 - jmums.mazums.ac.ir
Background and purpose: Human epidermal growth factor (hEGF) is a polypeptide of 53
amino acids with various medical application such as wound healing. The purpose of this …

A fibrin gel loaded with chitosan nanoparticles for local delivery of rhEGF: preparation and in vitro release studies

W Zhou, M Zhao, Y Zhao, Y Mou - Journal of Materials Science: Materials …, 2011 - Springer
Recombinant human epidermal growth factor (rhEGF) is known to stimulate cell proliferation
and accelerate wound healing. Direct delivery of rhEGF at the wound site in a sustained and …

Repair effect of diabetic ulcers with recombinant human epidermal growth factor loaded by sustained-release microspheres

XQ Dong, J Xu, WC Wang, H Luo, XF Liang… - Science in China Series …, 2008 - Springer
In this study the w/o/w extraction-evaporation technique was adopted to prepare poly (lactic-
co-glycolic acid)(PLGA) microspheres loading recombinant human epidermal growth factor …

Preparation of hydrogel embedded polymer-growth factor conjugated nanoparticles as a diabetic wound dressing

M Hajimiri, S Shahverdi, MA Esfandiari… - Drug development …, 2016 - Taylor & Francis
Context: Growth factors act in an integrated manner to promote the wound-healing process.
However, probably due to early inactivation of these molecules in the wound site, their …

[HTML][HTML] Optimization of secreted recombinant human epidermal growth factor production using pectate lyase B from Escherichia coli BL21 (DE3) by central composite …

S Sriwidodo, T Subroto, IP Maksum… - Journal of Pharmacy …, 2019 - journals.lww.com
Context: Human Epidermal Growth Factor (hEGF) is a potential therapeutic protein that has
been widely used as a healing agent for various chronic wounds. It induces the proliferation …