Homologous recombination (HR) is established as a significant contributor to double‐strand
break (DSB) repair in mammalian somatic cells; however, its role in mammalian germ cells …

The present study was designed to detect DNA repair response through the homologous
recombination pathway in mouse spermatogonial stem cells. Mouse spermatogonial stem …

Spermatogenesis is a complex developmental process. During this process, male germ cells
from spermatogonia to sperm cells encounter a number of DNA damages. The most severe …

This study was designed to obtain a better insight into the relative contribution of
homologous recombination (HR) and non-homologous end joining (NHEJ) to the repair of …

Mammalian somatic cells are known to repair DNA double-strand breaks (DSBs) by
nonhomologous end joining (NHEJ) and homologous recombination (HR); however, how …

In mammalian cells, the repair of DNA double-strand breaks (DSBs) occurs by both
homologous and non-homologous mechanisms. Indirect evidence, including that from gene …

A paradigm shift has occurred over the last few years in the understanding of homologous
recombination. It has long been known that DNA double-strand breaks (DSBs) in yeast are …

DNA double-strand break (DSB) processing was studied in mouse testicular extracts using a
defined DSB created by cleaving supercoiled pUC12 DNA at a unique site as the substrate …

In mammalian cells, chromosomal double-strand breaks are efficiently repaired, yet little is
known about the relative contributions of homologous recombination and illegitimate …

In male germ cells the repair of DNA double strand breaks (DSBs) differs from that described
for somatic cell lines. Irradiation induced immunofluorescent foci (IRIF's) signifying a double …