[HTML][HTML] The effects of PPAR-γ agonist pioglitazone on hippocampal cytokines, brain-derived neurotrophic factor, memory impairment, and oxidative stress status in …

F Beheshti, M Hosseini, M Hashemzehi… - Iranian Journal of …, 2019 - ncbi.nlm.nih.gov
Objective (s): The aim of current study was to evaluate improving effects of pioglitazone as
an agonist of peroxisome proliferator-activated receptor gamma (PPARγ), on brain-derived …

[HTML][HTML] Anticonvulsant and ameliorative effects of pioglitazone on cognitive deficits, inflammation and apoptosis in the hippocampus of rat pups exposed to febrile …

HA Hussein, A Moghimi… - Iranian journal of basic …, 2019 - ncbi.nlm.nih.gov
Objective (s): Pioglitazone (PGZ), a peroxisome proliferator-activated receptor gamma
(PPAR-γ) agonist, has significant neuroprotective effects and has been reported to regulate …

[HTML][HTML] Pioglitazone ameliorates lipopolysaccharide-induced behavioral impairment, brain inflammation, white matter injury and mitochondrial dysfunction in …

JH Yeh, KC Wang, A Kaizaki, JW Lee, HC Wei… - International Journal of …, 2021 - mdpi.com
Previous studies have demonstrated that pioglitazone, a peroxisome proliferator-activated
receptor gamma (PPARγ) agonist, inhibits ischemia-induced brain injury. The present study …

Phloridzin attenuates lipopolysaccharide-induced cognitive impairment via antioxidant, anti-inflammatory and neuromodulatory activities

SP Kamdi, A Raval, KT Nakhate - Cytokine, 2021 - Elsevier
Background Lipopolysaccharide (LPS) is known to produce neuroinflammation and memory
impairment. Although phloridzin (a phenolic phytoconstituent) shows antioxidant-and anti …

Neuroprotective effect of pioglitazone on acute phase changes induced by partial global cerebral ischemia in mice

B Medhi, R Aggarwal, A Chakrabarti - 2010 - nopr.niscpr.res.in
Present study was carried out to investigate the possible neuroprotective effect of
pioglitazone, an antidiabetic agent, peroxisome proliferator-activated receptor< img …

The effects of captopril on lipopolysaccharide induced learning and memory impairments and the brain cytokine levels and oxidative damage in rats

A Abareshi, M Hosseini, F Beheshti, F Norouzi… - Life sciences, 2016 - Elsevier
Aim Renin-angiotensin system has a role in inflammation and also involves in learning and
memory. In the present study, the effects of captopril on lipopolysaccharide (LPS) induced …

Role of nuclear receptor on regulation of BDNF and neuroinflammation in hippocampus of β-amyloid animal model of Alzheimer's disease

A Prakash, A Kumar - Neurotoxicity research, 2014 - Springer
Peroxisome proliferator-activated receptor-γ (PPAR-γ) agonists have been reported to
provide neuroprotective effects against neurodegenerative diseases. The current study was …

[HTML][HTML] Rosinidin attenuates lipopolysaccharide-induced memory impairment in rats: possible mechanisms of action include antioxidant and anti-inflammatory effects

S Alshehri, SS Imam - Biomolecules, 2021 - mdpi.com
The investigation aimed to evaluate the favourable effects of rosinidin in lipopolysaccharide
(LPS)-induced learning and memory impairment in rats. Adult Wistar rats (150–200 g) were …

Rosiglitazone attenuates amyloid beta and glial fibrillary acidic protein in the hippocampus and neuroinflammation associated learning and memory impairments in …

F Beheshti, M Hosseini… - Behavioural Brain …, 2023 - Elsevier
Objective The aim of the current study was to investigate the beneficial effects of
rosiglitazone (Rosi) on amyloid beta (Aβ) and glial fibrillary acidic protein (GFAP) in the …

Improvement in long term and visuo-spatial memory following chronic pioglitazone in mouse model of Alzheimer's disease

R Gupta, LK Gupta - Pharmacology Biochemistry and Behavior, 2012 - Elsevier
Peroxisome proliferator-activated receptor-gamma (PPAR-γ) agonists (thiazolidinediones)
are widely prescribed for the treatment of type-II diabetes mellitus. Recently, PPAR-γ …