Role of resident microbial communities in biofilm-related implant infections: recent insights and implications

MA Serbanescu, CG Apple… - Surgical Infections, 2023 - liebertpub.com
The use of medical implants continues to grow as the population ages. Biofilm-related
implant infection is the leading cause of medical implant failure and remains difficult to …

Environmental, microbiological, and immunological features of bacterial biofilms associated with implanted medical devices

M Caldara, C Belgiovine, E Secchi… - Clinical microbiology …, 2022 - Am Soc Microbiol
The spread of biofilms on medical implants represents one of the principal triggers of
persistent and chronic infections in clinical settings, and it has been the subject of many …

Polymicrobial biofilms related to dental implant diseases: unravelling the critical role of extracellular biofilm matrix

RC Costa, M Bertolini, BE Costa Oliveira… - Critical reviews in …, 2023 - Taylor & Francis
Biofilms are complex tri-dimensional structures that encase microbial cells in an extracellular
matrix comprising self-produced polymeric substances. The matrix rich in extracellular …

[HTML][HTML] Microbiota of Peri-Implant Healthy Tissues, Peri-Implant Mucositis, and Peri-Implantitis: A Comprehensive Review

F Di Spirito, F Giordano, MP Di Palo, F D'Ambrosio… - Microorganisms, 2024 - mdpi.com
Understanding the microbiological profiles of peri-implant conditions is crucial for
developing effective preventive and therapeutic strategies. This narrative review analyzes …

[HTML][HTML] Challenges in the microbiological diagnosis of implant-associated infections: A summary of the current knowledge

A Oliva, MC Miele, D Al Ismail, F Di Timoteo… - Frontiers in …, 2021 - frontiersin.org
Implant-associated infections are characterized by microbial biofilm formation on implant
surface, which renders the microbiological diagnosis challenging and requires, in the …

[HTML][HTML] Emerging Issues and Initial Insights into Bacterial Biofilms: From Orthopedic Infection to Metabolomics

R Mirzaei, D Campoccia, S Ravaioli, CR Arciola - Antibiotics, 2024 - mdpi.com
Bacterial biofilms, enigmatic communities of microorganisms enclosed in an extracellular
matrix, still represent an open challenge in many clinical contexts, including orthopedics …

Implants induce a new niche for microbiomes

TH Jakobsen, SR Eickhardt, AG Gheorghe, C Stenqvist… - Apmis, 2018 - Wiley Online Library
Although much work is being done to develop new treatments, research and knowledge
regarding factors underlying implant‐related microbial colonization leading to infection are …

High-throughput sequencing of microbial diversity in implant-associated infection

X Wang, X Hu, K Deng, X Cheng, J Wei, M Jiang… - Infection, Genetics and …, 2016 - Elsevier
Few molecular studies have shown that the number of bacterial species in implant-
associated infection may have been underestimated. To determine the actual microbial …

[HTML][HTML] Improve integration of in vitro biofilm body of knowledge to support clinical breakthroughs in surgical site infection

S Irwin, BW Mackenzie, BG Matthews… - … Global Research & …, 2021 - journals.lww.com
Prosthetics increase the risk of deep surgical site infections in procedures intended to
restore function. In orthopaedics, prosthetic joint infections can lead to repetitive surgeries …

[HTML][HTML] A review on antimicrobial strategies in mitigating biofilm-associated infections on medical implants.

L Kadirvelu, SS Sivaramalingam, D Jothivel… - Current Research in …, 2024 - Elsevier
Biomedical implants are crucial in providing support and functionality to patients with
missing or defective body parts. However, implants carry an inherent risk of bacterial …