[HTML][HTML] Statins use and COVID-19 outcomes in hospitalized patients

SK Ayeh, EJ Abbey, BAA Khalifa, RD Nudotor… - PLoS …, 2021 - journals.plos.org
Background There is an urgent need for novel therapeutic strategies for reversing COVID-19-
related lung inflammation. Recent evidence has demonstrated that the cholesterol-lowering …

Association between statin use and outcomes in patients with coronavirus disease 2019 (COVID-19): a nationwide cohort study

JH Butt, TA Gerds, M Schou, K Kragholm, M Phelps… - BMJ open, 2020 - bmjopen.bmj.com
Objective To investigate the association between recent statin exposure and risk of severe
COVID-19 infection and all-cause mortality in patients with COVID-19 in Denmark. Design …

[HTML][HTML] The effect of statins on clinical outcome among hospitalized patients with COVID-19: a multi-centric cohort study

S Umakanthan, S Senthil, S John… - Frontiers in …, 2022 - frontiersin.org
The coronavirus disease-2019 (COVID-19) is caused by SARS-CoV-2, leading to acute
respiratory distress syndrome (ARDS), thrombotic complications, and myocardial injury …

[HTML][HTML] Statin use is associated with lower disease severity in COVID-19 infection

WYT Tan, BE Young, DC Lye, DEK Chew, R Dalan - Scientific Reports, 2020 - nature.com
We aim to study the association of hyperlipidemia and statin use with COVID-19 severity. We
analysed a retrospective cohort of 717 patients admitted to a tertiary centre in Singapore for …

The use of statins was associated with reduced COVID-19 mortality: a systematic review and meta-analysis

KS Wu, PC Lin, YS Chen, TC Pan, PL Tang - Annals of Medicine, 2021 - Taylor & Francis
Background Statins are widely used to treat people with metabolic and cardiovascular
disorders. The effect of statins on coronavirus disease 2019 (COVID-19) is unclear. To …

[HTML][HTML] The protective association between statins use and adverse outcomes among COVID-19 patients: a systematic review and meta-analysis

R Chow, J Im, N Chiu, L Chiu, R Aggarwal, J Lee… - PLoS …, 2021 - journals.plos.org
Introduction Statins may reduce a cytokine storm, which has been hypothesized as a
possible mechanism of severe COVID-19 pneumonia. The aim of this study was to conduct a …

Beneficial effect of statins in COVID-19–related outcomes—brief report: a national population-based cohort study

HY Lee, J Ahn, J Park, C Kyung Kang… - … , and vascular biology, 2021 - Am Heart Assoc
Objective: Although statins are widely prescribed lipid-lowering drugs, there are concerns
about the safety of their use in the context of coronavirus disease 2019 (COVID-19), since …

Statin use and mortality in COVID-19 patients: Updated systematic review and meta-analysis

A Kollias, KG Kyriakoulis, IG Kyriakoulis, T Nitsotolis… - Atherosclerosis, 2021 - Elsevier
Background and aims Statin therapy is administered to patients with high cardiovascular
risk. These patients are also at risk for severe course of coronavirus disease 2019 (COVID …

Association of pre-admission statin use with reduced in-hospital mortality in COVID-19

SR Chacko, R DeJoy III, KB Lo, J Albano… - The American Journal of …, 2021 - Elsevier
Abstract Background Coronavirus disease-19 (COVID-19) infection is associated with an
uncontrolled systemic inflammatory response. Statins, given their anti-inflammatory …

[HTML][HTML] Decreased mortality rate among COVID-19 patients prescribed statins: data from electronic health records in the US

I Marić, T Oskotsky, I Kosti, B Le, RJ Wong… - Frontiers in …, 2021 - frontiersin.org
The severe respiratory illness due to SARS-CoV-2, the virus responsible for coronavirus
disease 2019 (COVID-19), is triggered by an intense pro-inflammatory host response …