Cytokine networks in neuroinflammation
B Becher, S Spath, J Goverman - Nature Reviews Immunology, 2017 - nature.com
Cytokines provide cells with the ability to communicate with one another and orchestrate
complex multicellular behaviour. There is an emerging understanding of the role that …
complex multicellular behaviour. There is an emerging understanding of the role that …
Neuro-immune crosstalk in CNS diseases
M Kerschensteiner, E Meinl, R Hohlfeld - Neuroscience, 2009 - Elsevier
Immune cells infiltrate the CNS in many neurological diseases with a primary or secondary
inflammatory component. In the CNS, immune cells employ shared mediators to promote …
inflammatory component. In the CNS, immune cells employ shared mediators to promote …
Cross-talk of the CNS with immune cells and functions in health and disease
A Matejuk, AA Vandenbark, H Offner - Frontiers in neurology, 2021 - frontiersin.org
The immune system's role is much more than merely recognizing self vs. non-self and
involves maintaining homeostasis and integrity of the organism starting from early …
involves maintaining homeostasis and integrity of the organism starting from early …
[HTML][HTML] Neuroinflammation: ways in which the immune system affects the brain
RM Ransohoff, D Schafer, A Vincent, NE Blachère… - …, 2015 - Elsevier
Neuroinflammation is the response of the central nervous system (CNS) to disturbed
homeostasis and typifies all neurological diseases. The main reactive components of the …
homeostasis and typifies all neurological diseases. The main reactive components of the …
The role of peripheral immune cells in the CNS in steady state and disease
The CNS is protected by the immune system, including cells that reside directly within the
CNS and help to ensure proper neural function, as well as cells that traffic into the CNS with …
CNS and help to ensure proper neural function, as well as cells that traffic into the CNS with …
Neuroinflammation: an integrating overview of reactive‐Neuroimmune cell interactions in health and disease
R Kölliker-Frers, L Udovin… - Mediators of …, 2021 - Wiley Online Library
The concept of central nervous system (CNS) inflammation has evolved over the last
decades. Neuroinflammation is the response of reactive CNS components to altered …
decades. Neuroinflammation is the response of reactive CNS components to altered …
The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases
Classical knowledge distinguishes between inflammatory and non-inflammatory diseases of
the brain. Either the immune system acts on the CNS and initiates a damage cascade, as in …
the brain. Either the immune system acts on the CNS and initiates a damage cascade, as in …
How the immune system shapes neurodegenerative diseases
HD Mason, DB McGavern - Trends in neurosciences, 2022 - cell.com
Neurodegenerative diseases are a major cause of death and disability worldwide and are
influenced by many factors including age, genetics, and injuries. While these diseases are …
influenced by many factors including age, genetics, and injuries. While these diseases are …
An inflammation-centric view of neurological disease: beyond the neuron
Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …
Neurodegeneration triggers peripheral immune cell recruitment into the forebrain
M Scheld, BJ Rüther, R Große-Veldmann… - Journal of …, 2016 - Soc Neuroscience
Brain-intrinsic degenerative cascades have been proposed to be an initial factor driving
lesion formation in multiple sclerosis (MS). Here, we identify neurodegeneration as a potent …
lesion formation in multiple sclerosis (MS). Here, we identify neurodegeneration as a potent …