During the release of sperm at spermiation, a biologically active F5-peptide, which can
disrupt the Sertoli cell tight junction (TJ) permeability barrier, is produced at the site of the …

Focal adhesion kinase (FAK), as its name implied, is an important mediator of integrin-based
signaling function in mammalian cells at the focal adhesion complex (FAC, also known as …

Germ cell transport across the seminiferous epithelium during spermatogenesis requires the
intricate coordination of cell junctions, signaling proteins, and both actin-and microtubule …

During spermatogenesis, step 1 spermatids (round spermatids) derive from spermatocytes
following meiosis I and II at stage XIV of the epithelial cycle begin a series of morphological …

The blood-testis barrier (BTB) is an important ultrastructure in the testis. A delay in its
assembly during postnatal development leads to meiotic arrest. Also, a disruption of the BTB …

During spermatogenesis, preleptotene spermatocytes residing near the basement
membrane of the seminiferous tubule must traverse the blood-testis barrier (BTB) at stage …

In the testis, spermatids are polarized cells, with their heads pointing toward the basement
membrane during maturation. This polarity is crucial to pack the maximal number of …

During spermatogenesis, the molecular mechanism that confers spermatid adhesion to the
Sertoli cell at the apical ectoplasmic specialization (apical ES), a testis-specific F-actin-rich …

During spermatogenesis, developing spermatids and preleptotene spermatocytes are
transported across the adluminal compartment and the blood-testis barrier (BTB) …

Formin is one of the two major classes of actin binding proteins (ABPs) with nucleation and
polymerization activity. However, despite advances in our understanding of its biochemical …