Hippocampal volume shrinks in late adulthood, but the neuromolecular factors that trigger
hippocampal decay in aging humans remains a matter of speculation. In rodents, brain …

The beneficial effects of brain-derived neurotrophic factor (BDNF)—a member of the
neurotrophin family—on cognitive function or dementia are well established in both rodents …

Brain derived neurotrophic factor (BDNF) seems to be involved in regulation of synaptic
plasticity and neurogenesis. BDNF plasma and serum levels have been associated with …

Late adulthood is associated with increased hippocampal atrophy and dysfunction. Although
there are multiple paths by which hippocampal deterioration occurs in late life, the authors …

Background Brain-derived neurotrophic factor (BDNF) is an activity-dependent secreted
protein that is critical to organization of neuronal networks and synaptic plasticity, especially …

It is known since a long time that the hippocampus is sensitive to aging. Thus, there is a
reduction in the hippocampal volume during aging. This age-related volume reduction is …

The expression of the neurotrophic factor BDNF increases during learning-related events
and is decreased in the hippocampus of Alzheimer's Disease patients, suggesting that it …

Alzheimer's disease may be due to a deficiency in neurotrophin protein or receptor
expression. Consistent with this hypothesis, a reduction in BDNF mRNA expression has …

Aims: Our purpose was to study the link between serum brain-derived neurotrophic factor
(BDNF) levels and neuropsychological functioning through the Texas Alzheimer's Research …

Aging impairs the competence of the hippocampus for synaptic reorganization after injury.
This potentially is due to the inability of the aging hippocampus to up‐regulate the critical …