This study prepared a colloidal gold-based immunochromatographic strip (CG-ICS) for the
detection of 5-fluorouracil (5-FU) in human plasma, for therapeutic drug monitoring. Three …

Fluorouracil (5-FU) is an effective anticancer drug widely used in cancer treatment. In this
study, two 5-FU derivatives containing a spacer arm with the carboxylic group at the end …

Abstract Paclitaxel (PTX), methotrexate (MTX), and 5-fluorouracil (5-FU) are commonly-used
small molecule anti-tumor drugs for breast cancer. Unfortunately, drug resistance occurs …

Objective To develop a robust liquid chromatography-tandem mass spectrometric (LC-
MS/MS) method for determination of 5-fluorouracil (5-FU) in blood plasma and evaluate the …

A high-performance liquid chromatography (HPLC) method was developed for the
determination of 5-fluorouracil (5-FU) in 5-FU injection and human serum. A Nova-park C18 …

A simple and sensitive reversed-phase HPLC method with UV detection was developed and
validated for the quantitation of 5-fluorouracil (5-FU) in human plasma. After acidification and …

5-Fluorouracil (5-FU) is one of the most widely used antineoplastic drugs. It can be therefore
considered to be a model compound for the identification of exposure routes during …

Fluorouracil (5-FU) has a broad spectrum of anti-tumor activity, widely applied to the
treatment of cancers. However, it is necessary to determine the plasma concentration of 5 …

Objective: To establish a particular, sensitive and accurate High Performance Liquid
Chromatography (HPLC) technique for the specific and effective analysis of 5-Fluorouracil (5 …

In order to observe the biodistribution of 5-fluorouracil (5-FU) and its main metabolites in
different kinds of tissue (tumor, liver, kidney, spleen, mucosa, lungs, heart, peritoneum …