Multiple Intermediates in the Detergent-Induced Fusion of Lipid Vesicles
The structure, dynamics and function of lipid vesicles are heavily influenced by a range of
physical forces, local microenvironmental effects and interactions with perturbative …
physical forces, local microenvironmental effects and interactions with perturbative …
Controlled fusion of synthetic lipid membrane vesicles
M Ma, D Bong - Accounts of chemical research, 2013 - ACS Publications
Lipid membrane fusion is a fundamental noncovalent transformation as well as a central
process in biology. The complex and highly controlled biological machinery of fusion has …
process in biology. The complex and highly controlled biological machinery of fusion has …
Unveiling the multi-step solubilization mechanism of sub-micron size vesicles by detergents
The solubilization of membranes by detergents is critical for many technological applications
and has become widely used in biochemistry research to induce cell rupture, extract cell …
and has become widely used in biochemistry research to induce cell rupture, extract cell …
Membrane fusion of pH-sensitive liposomes–a quantitative study using giant unilamellar vesicles
Drug delivery systems based on liposome carriers that are designed for induction of
membrane fusion in response to the microenvironment have been investigated for more …
membrane fusion in response to the microenvironment have been investigated for more …
[HTML][HTML] Crowding-induced morphological changes in synthetic lipid vesicles determined using smFRET
Lipid vesicles are valuable mesoscale molecular confinement vessels for studying
membrane mechanics and lipid-protein interactions, and they have found utility among bio …
membrane mechanics and lipid-protein interactions, and they have found utility among bio …
Salt-induced lipid transfer between colloidal supported lipid bilayers
We show that a coordinated interplay between mesoscale colloidal interactions and
molecular-scale membrane perturbations affords a novel material platform to controllably …
molecular-scale membrane perturbations affords a novel material platform to controllably …
Integrated suspended lipid membrane platform: Harnessing amperometric and single-molecule capabilities for deep insights into fusion dynamics
JS Weerakkody, S Thoduvayil, S Ramakrishnan - Biophysical Journal, 2024 - cell.com
Cellular plasma membranes are central to molecular transport and signaling. Traditional
models, reliant on lipid mixing and content release techniques, provide limited clarity on the …
models, reliant on lipid mixing and content release techniques, provide limited clarity on the …
Fusion modifies the material properties of membranes
RB Lira, C Richards, RRM Cavalcanti, C Aberg… - Biophysical …, 2023 - cell.com
Membrane fusion is a ubiquitous process in biology and potentially an alternative to
endocytic internalization pathways in drug delivery. Due to its high complexity, assays have …
endocytic internalization pathways in drug delivery. Due to its high complexity, assays have …
Size-dependent, stochastic nature of lipid exchange between nano-vesicles and model membranes
The interaction of nanoscale lipid vesicles with cell membranes is of fundamental
importance for the design and development of vesicular drug delivery systems. Here, we …
importance for the design and development of vesicular drug delivery systems. Here, we …
Membrane-embedded nanoparticles induce lipid rearrangements similar to those exhibited by biological membrane proteins
RC Van Lehn, A Alexander-Katz - The Journal of Physical …, 2014 - ACS Publications
Amphiphilic monolayer-protected gold nanoparticles (NPs) have recently been shown to
spontaneously fuse with lipid bilayers under typical physiological conditions. The final …
spontaneously fuse with lipid bilayers under typical physiological conditions. The final …