Designing antimicrobial peptides using deep learning and molecular dynamic simulations
Q Cao, C Ge, X Wang, PJ Harvey… - Briefings in …, 2023 - academic.oup.com
With the emergence of multidrug-resistant bacteria, antimicrobial peptides (AMPs) offer
promising options for replacing traditional antibiotics to treat bacterial infections, but …
promising options for replacing traditional antibiotics to treat bacterial infections, but …
Deep learning for novel antimicrobial peptide design
C Wang, S Garlick, M Zloh - Biomolecules, 2021 - mdpi.com
Antimicrobial resistance is an increasing issue in healthcare as the overuse of antibacterial
agents rises during the COVID-19 pandemic. The need for new antibiotics is high, while the …
agents rises during the COVID-19 pandemic. The need for new antibiotics is high, while the …
Deep learning regression model for antimicrobial peptide design
J Witten, Z Witten - BioRxiv, 2019 - biorxiv.org
Antimicrobial peptides (AMPs) are naturally occurring or synthetic peptides that show
promise for treating antibiotic-resistant pathogens. Machine learning techniques are …
promise for treating antibiotic-resistant pathogens. Machine learning techniques are …
AMPlify: attentive deep learning model for discovery of novel antimicrobial peptides effective against WHO priority pathogens
Background Antibiotic resistance is a growing global health concern prompting researchers
to seek alternatives to conventional antibiotics. Antimicrobial peptides (AMPs) are attracting …
to seek alternatives to conventional antibiotics. Antimicrobial peptides (AMPs) are attracting …
[HTML][HTML] Rational discovery of antimicrobial peptides by means of artificial intelligence
P Ruiz Puentes, MC Henao, J Cifuentes… - Membranes, 2022 - mdpi.com
Antibiotic resistance is a worldwide public health problem due to the costs and mortality
rates it generates. However, the large pharmaceutical industries have stopped searching for …
rates it generates. However, the large pharmaceutical industries have stopped searching for …
AMP‐BERT: Prediction of antimicrobial peptide function based on a BERT model
Antimicrobial resistance is a growing health concern. Antimicrobial peptides (AMPs) disrupt
harmful microorganisms by nonspecific mechanisms, making it difficult for microbes to …
harmful microorganisms by nonspecific mechanisms, making it difficult for microbes to …
Recent progress in the discovery and design of antimicrobial peptides using traditional machine learning and deep learning
Antimicrobial resistance has become a critical global health problem due to the abuse of
conventional antibiotics and the rise of multi-drug-resistant microbes. Antimicrobial peptides …
conventional antibiotics and the rise of multi-drug-resistant microbes. Antimicrobial peptides …
[HTML][HTML] Ab initio designed antimicrobial peptides against Gram-negative bacteria
SS Bobde, FM Alsaab, G Wang… - Frontiers in …, 2021 - frontiersin.org
Antimicrobial peptides (AMPs) are ubiquitous amongst living organisms and are part of the
innate immune system with the ability to kill pathogens directly or indirectly by modulating …
innate immune system with the ability to kill pathogens directly or indirectly by modulating …
[HTML][HTML] Application of a deep generative model produces novel and diverse functional peptides against microbial resistance
Antimicrobial resistance could threaten millions of lives in the immediate future.
Antimicrobial peptides (AMPs) are an alternative to conventional antibiotics practice against …
Antimicrobial peptides (AMPs) are an alternative to conventional antibiotics practice against …
Intelligent de novo design of novel antimicrobial peptides against antibiotic-resistant bacteria strains
Because of the growing number of clinical antibiotic resistance cases in recent years, novel
antimicrobial peptides (AMPs) may be ideal for next-generation antibiotics. This study …
antimicrobial peptides (AMPs) may be ideal for next-generation antibiotics. This study …
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