[HTML][HTML] 米托蒽醌甲磺酸盐预处理脂肪间充质干细胞对犬糖尿病的治疗效果评价
谭宁， 李巴仑， 韩苗， 李琛琛， 景远翔， 寇正， 李娜… - 畜牧兽医学报, 2024 - html.rhhz.net
本研究在高脂饮食(high-fat diet, HFD) 饲喂和链脲佐菌素(streptozotin, STZ)
注射的联合作用下成功建立小鼠及犬糖尿病模型, 旨在探究米托蒽醌甲磺酸盐(mitoquionl …
注射的联合作用下成功建立小鼠及犬糖尿病模型, 旨在探究米托蒽醌甲磺酸盐(mitoquionl …
犬骨髓间充质干细胞体外诱导分化为胰岛样细胞的研究
谢婷， 欧阳建， 陈军浩， 王晶， 刘勇， 顾香芳 - 中国糖尿病杂志, 2010 - cqvip.com
目的研究犬骨髓间充质干细胞(MSC) 体外诱导分化为胰岛样细胞的可能性. 方法分离纯化犬骨髓
MSC, 予EGF, bFGF 和β 细胞调节素, 尼克酰胺, B27 添加剂诱导. 双硫腙染色, West—ernblot …
MSC, 予EGF, bFGF 和β 细胞调节素, 尼克酰胺, B27 添加剂诱导. 双硫腙染色, West—ernblot …
Investigating the route of administration and efficacy of adipose tissue-derived mesenchymal stem cells and conditioned medium in type 1 diabetic mice
Abstract Type 1 diabetes (T1D) is a chronic autoimmune disease destroying the insulin-
producing beta cells. Recently, stem cell therapy has been tested to treat T1D. In the present …
producing beta cells. Recently, stem cell therapy has been tested to treat T1D. In the present …
自体脂肪间充质干细胞移植对糖尿病大鼠肾功能的改善作用
闵小春， 伍婷婷， 杞少华， 姚维琪， 武栋成 - 实用医学杂志, 2015 - cqvip.com
目的: 利用动物模型研究自体脂肪间充质干细胞(adipose. derivedmesenchymalstemcells,
ADMSCs) 移植对糖尿病大鼠肾功能的改善作用. 方法: sD 大鼠连续5d 腹腔注射40mg/kg …
ADMSCs) 移植对糖尿病大鼠肾功能的改善作用. 方法: sD 大鼠连续5d 腹腔注射40mg/kg …
[HTML][HTML] Diabetic microenvironment preconditioning of adipose tissue-derived mesenchymal stem cells enhances their anti-diabetic, anti-long-term complications, and …
W Su, S Yu, Y Yin, B Li, J Xue, J Wang, Y Gu… - Stem Cell Research & …, 2022 - Springer
Abstract Background Mesenchymal stem cells (MSCs) exert anti-diabetic effects and
improve long-term complications via secretory effects that regulate macrophage polarisation …
improve long-term complications via secretory effects that regulate macrophage polarisation …
Adipose tissue-derived mesenchymal stromal cells efficiently differentiate into insulin-producing cells in pancreatic islet microenvironment both in vitro and in vivo
Background aims Differentiation or reprogramming of stem cells could be achieved by
remodulating the microenvironment, which regulates the fate of cells by soluble factors and …
remodulating the microenvironment, which regulates the fate of cells by soluble factors and …
[HTML][HTML] Reprogramming adipose mesenchymal stem cells into islet β-cells for the treatment of canine diabetes mellitus
P Dai, G Qi, H Xu, M Zhu, J Li, Y Chen, L Zhang… - Stem Cell Research & …, 2022 - Springer
Background Islet transplantation is an excellent method for the treatment of type I diabetes
mellitus. However, due to the limited number of donors, cumbersome isolation and …
mellitus. However, due to the limited number of donors, cumbersome isolation and …
Adipose-derived mesenchymal stem cells ameliorate hyperglycemia through regulating hepatic glucose metabolism in type 2 diabetic rats
M Xie, HJ Hao, YU Cheng, ZY Xie, YQ Yin… - Biochemical and …, 2017 - Elsevier
Infusion of mesenchymal stem cells (MSCs) has been identified in the rapid alleviation in
hyperglycemia of diabetic individuals, but the mechanism involved has not been adequately …
hyperglycemia of diabetic individuals, but the mechanism involved has not been adequately …
人脐带间充质干细胞对猕猴糖尿病治疗效果的研究
阮光萍， 刘菊芬， 李自安， 王金祥， 庞荣清… - … 细胞与干细胞杂志: 电子版, 2017 - cqvip.com
目的通过用人脐带间充质干细胞(huMSCs) 治疗猕猴糖尿病模型观察其血糖的变化. 方法猕猴9
只, 分为对照组3 只和模型组6 只, 模型组通过高糖高脂饮食及静脉注射链尿佐菌素(STZ) …
只, 分为对照组3 只和模型组6 只, 模型组通过高糖高脂饮食及静脉注射链尿佐菌素(STZ) …
大鼠脂肪间充质干细胞体外转染为胰岛素分泌细胞的实验研究
葛亮， 赵建勇， 孙诚谊， 贾文胜 - 中华消化外科杂志, 2013 - cqvip.com
目的探讨脂肪间充质干细胞(ADMSCs) 体外转染成为胰岛素分泌细胞的可能性及其在不同浓度
葡萄糖环境下的胰岛素分泌情况. 方法以未转染的ADMSCs 作为对照组, 含有PcDNA3-1 …
葡萄糖环境下的胰岛素分泌情况. 方法以未转染的ADMSCs 作为对照组, 含有PcDNA3-1 …