[HTML][HTML] PeruNPDB: The Peruvian natural products database for in silico drug screening

HL Barazorda-Ccahuana, LG Ranilla… - Scientific Reports, 2023 - nature.com
Since the number of drugs based on natural products (NPs) represents a large source of
novel pharmacological entities, NPs have acquired significance in drug discovery. Peru is …

[HTML][HTML] Progress and impact of Latin American natural product databases

A Gómez-García, JL Medina-Franco - Biomolecules, 2022 - mdpi.com
Natural products (NPs) are a rich source of structurally novel molecules, and the chemical
space they encompass is far from being fully explored. Over history, NPs have represented a …

[HTML][HTML] Advances in computational approaches for drug discovery based on natural products

JL Medina-Franco - Revista latinoamericana de química, 2013 - scielo.org.mx
Drug discovery based on natural products has a long successful history. To further advance
the identification of new drugs from compounds of natural origin, natural product research is …

[HTML][HTML] Navigating the chemical space and chemical multiverse of a unified Latin American natural product database: LANaPDB

A Gómez-García, DAA Jiménez, WJ Zamora… - Pharmaceuticals, 2023 - mdpi.com
The number of databases of natural products (NPs) has increased substantially. Latin
America is extraordinarily rich in biodiversity, enabling the identification of novel NPs, which …

[HTML][HTML] SANCDB: a South African natural compound database

R Hatherley, DK Brown, TM Musyoka… - Journal of …, 2015 - Springer
Abstract Background Natural products (NPs) are important to the drug discovery process. NP
research efforts are expanding world-wide and South Africa is no exception to this. While …

[HTML][HTML] BIOFACQUIM: a Mexican compound database of natural products

BA Pilón-Jiménez, FI Saldívar-González… - Biomolecules, 2019 - mdpi.com
Compound databases of natural products have a major impact on drug discovery projects
and other areas of research. The number of databases in the public domain with compounds …

Towards a unified Latin American natural products database: LANaPD

JL Medina-Franco - Future Science OA, 2020 - Taylor & Francis
Around the world, the number of compound databases of natural products in the public
domain is rising. This is in line with the increasing synergistic combination of natural product …

[HTML][HTML] Latin American databases of natural products: biodiversity and drug discovery against SARS-CoV-2

MJ Núñez, BI Díaz-Eufracio, JL Medina-Franco… - RSC …, 2021 - pubs.rsc.org
In this study, we evaluated 3444 Latin American natural products using cheminformatic
tools. We also characterized 196 compounds for the first time from the flora of El Salvador …

NPASS: natural product activity and species source database for natural product research, discovery and tool development

X Zeng, P Zhang, W He, C Qin, S Chen… - Nucleic acids …, 2018 - academic.oup.com
There has been renewed interests in the exploration of natural products (NPs) for drug
discovery, and continuous investigations of the therapeutic claims and mechanisms of …

[HTML][HTML] Applications of virtual screening in bioprospecting: facts, shifts, and perspectives to explore the chemo-structural diversity of natural products

K Santana, LD Do Nascimento, A Lima e Lima… - Frontiers in …, 2021 - frontiersin.org
Natural products are continually explored in the development of new bioactive compounds
with industrial applications, attracting the attention of scientific research efforts due to their …