[HTML][HTML] Cytomegalovirus cell-mediated immunity: ready for routine use?

O Bestard, H Kaminski, L Couzi… - Transplant …, 2023 - frontierspartnerships.org
Utilizing assays that assess specific T-cell-mediated immunity against cytomegalovirus
(CMV) holds the potential to enhance personalized strategies aimed at preventing and …

Clinical experience with immune monitoring for cytomegalovirus in solid-organ transplant recipients

O Manuel - Current infectious disease reports, 2013 - Springer
Novel strategies are needed to further reduce the burden of cytomegalovirus (CMV) disease
in solid-organ transplant (SOT) recipients. Measurement of the specific cell-mediated …

State-of-the-art monitoring of cytomegalovirus-specific cell-mediated immunity after organ transplant: a primer for the clinician

A Egli, A Humar, D Kumar - Clinical infectious diseases, 2012 - academic.oup.com
Cytomegalovirus (CMV) is one of the most common infections after solid organ
transplantation. Improved assays to predict viral replication and disease would help refine …

Utility of cytomegalovirus cell-mediated immunity assays in solid organ transplantation

VG Hall, A Humar, D Kumar - Journal of Clinical Microbiology, 2022 - Am Soc Microbiol
Cytomegalovirus (CMV) is one of the most important viral complications after solid organ
transplantation (SOT). Current preventive and management strategies rely primarily on …

Immune-based monitoring for cytomegalovirus infection in solid organ transplantation: is it ready for clinical primetime?

D Melendez, RR Razonable - Expert review of clinical immunology, 2014 - Taylor & Francis
The impact of CMV infection and disease in solid organ transplant (SOT) recipients
continues despite remarkable improvements in its prevention and management with antiviral …

[HTML][HTML] An interventional study using cell-mediated immunity to personalize therapy for cytomegalovirus infection after transplantation

D Kumar, M Mian, L Singer, A Humar - American Journal of Transplantation, 2017 - Elsevier
Cell-mediated immune responses predict clinical cytomegalovirus (CMV) events but have
not been adopted into routine practice due to lack of interventional studies. Our objective …

Utility of CMV-specific immune monitoring for the management of CMV in solid organ transplant recipients: a clinical update

K Prakash, A Chandorkar, KK Saharia - Diagnostics, 2021 - mdpi.com
Cytomegalovirus (CMV) is one of the most important opportunistic infections in solid organ
transplant (SOT) recipients. However, current techniques used to predict risk for CMV …

Immune monitoring for CMV in transplantation

MK Yong, SR Lewin, O Manuel - Current infectious disease reports, 2018 - Springer
Abstract Purpose of Review Immune monitoring to determine when and how the recovery of
cytomegalovirus (CMV)-specific T-cells occurs post-transplantation may help clinicians to …

Assessment of cytomegalovirus-specific cell-mediated immunity for the prediction of cytomegalovirus disease in high-risk solid-organ transplant recipients: a …

O Manuel, S Husain, D Kumar, C Zayas… - Clinical infectious …, 2013 - academic.oup.com
Background. Cytomegalovirus (CMV) disease remains an important problem in solid-organ
transplant recipients, with the greatest risk among donor CMV-seropositive, recipient …

[HTML][HTML] Cell-mediated immunity to predict cytomegalovirus disease in high-risk solid organ transplant recipients

D Kumar, S Chernenko, G Moussa, I Cobas… - American journal of …, 2009 - Elsevier
Late-onset cytomegalovirus (CMV) disease commonly occurs after discontinuation of
antiviral prophylaxis. We determined the utility of testing CD8+ T-cell response against CMV …