Background Twin studies have provided evidence that both genetic and environmental
factors contribute to schizophrenia (SZ) risk. Heritability estimates of SZ in twin samples …

Background The magnitude of heritability of schizophrenia remains controversial, due in part
to limitations of estimates derived from index twin pairs exclusively. We applied structural …

Context There are many published twin studies of schizophrenia. Although these studies
have been reviewed previously, to our knowledge, no review has provided quantitative …

It has been known for a long time that schizophrenia and several related psychopathological
traits aggregate in families on a common genetic basis. Improved methodology of recent …

Estimates of heritability of psychiatric disorders quantify the genetic contribution to their
etiology. Estimation of these parameters requires affected status on probands and their …

Background The polygenic risk score (PRS) for schizophrenia, derived from very large
numbers of weakly associated genetic markers, has been repeatedly shown to be robustly …

This study investigated the factor structure and etiology of four self-report schizotypy
questionnaires during young adulthood (age 18–27) in 98 monozygotic and 59 same-sex …

Epidemiologists and geneticists have tended to explore their respective domains
independently, and as a consequence, these fields have drifted apart. The aim of this article …

While twin concordances for schizophrenia have been used to estimate heritability and to
develop genetic models, concordances in subtypes of monozygotic (MZ) twins can also be …

Schizophrenia is a severe mental disorder affecting∼ 1% of the world's population. Here,
we report the results from a three-stage genomewide screen performed in a study sample …